SCHEMBL3669752

SCHEMBL3669752

CCc1ccc(O)c(C(C)=Cc2ccccc2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.46
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 1/20 0.41
USP2 O75604 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
HTT P42858 1/20 0.41
HSD17B10 Q99714 1/20 0.41
HNF4A P41235 2/20 0.41
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
KLKB1 P03952 1/20 0.38
CTSB P07858 1/20 0.38
MMP9 P14780 1/20 0.38
DNMT1 P26358 1/20 0.38
DNMT3B Q9UBC3 1/20 0.38
DNMT3L Q9UJW3 1/20 0.38
DNMT3A Q9Y6K1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3634455 0.84 MEN1 (0.40) ALDH1A1HTTMEN1KMT2ATSHR
SCHEMBL3634451 0.84 MEN1 (0.40) ALDH1A1HTTMEN1KMT2ATSHR
SCHEMBL4530038 0.84 GABRA1 (0.47) TRPA1ALDH1A1KDM4EUSP2MAPT
SCHEMBL3668138 0.79 CSNK2A1 (0.50) TRPA1KDM4EMAPTHNF4AMEN1
SCHEMBL11203024 0.76 MAPT (0.47) TRPA1ALDH1A1KDM4EMAPTHSD17B10
SCHEMBL30495367 0.76 MAPT (0.47) TRPA1ALDH1A1KDM4EMAPTHSD17B10
SCHEMBL10973737 0.76 MAPT (0.47) TRPA1ALDH1A1KDM4EMAPTHSD17B10
SCHEMBL6546875 0.75 ESR1 (0.50) ALDH1A1MAPTMEN1KMT2ATSHR
SCHEMBL21467261 0.72 ALDH1A1 (0.51) TRPA1ALDH1A1KDM4EUSP2GAA
SCHEMBL4538257 0.72 ALDH1A1 (0.48) TRPA1ALDH1A1KDM4EUSP2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2162518-A1 LUBRICANT COMPOSITIONS STABILIZED WITH STYRENATED PHENOLIC ANTIOXIDANT CHEMTURA CORPORATION (US) 2010-03-17 EP disclosed
WO-2009009293-A1 LUBRICANT COMPOSITIONS STABILIZED WITH STYRENATED PHENOLIC ANTIOXIDANT CHEMTURA CORPORATION (US) 2009-01-15 WO disclosed
US-20090011961-A1 Lubricant compositions stabilized with styrenated phenolic antioxidant CROMPTON HOLDING CORPORATION 2009-01-08 US disclosed