Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHAT | P28329 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | HNF4A | P41235 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9495152 | 0.83 | TTR (0.50) | CHATPTGS1PTGS2TTRALOX5 | |
| SCHEMBL18442131 | 0.80 | TRPA1 (0.47) | CHATPTGS1PTGS2TTRALOX5 | |
| SCHEMBL11774465 | 0.75 | SLC22A8 (0.39) | TRPA1 | |
| SCHEMBL9495620 | 0.74 | TUBB1 (0.59) | MAPTTRPA1MEN1ALDH1A1KMT2A | |
| SCHEMBL17097111 | 0.74 | TTR (0.53) | CHATPTGS1PTGS2TTRALOX5 | |
| SCHEMBL8770707 | 0.73 | TYR (0.48) | ALOX5GAAMAPTMEN1ALDH1A1 | |
| SCHEMBL20488356 | 0.73 | ALOX5 (0.56) | CHATPTGS1PTGS2TTRALOX5 | |
| SCHEMBL6546307 | 0.71 | CHAT (0.51) | CHATPTGS1PTGS2TTRALOX5 | |
| SCHEMBL8416884 | 0.71 | TRPA1 (0.53) | CHATPTGS1PTGS2TTRALOX5 | |
| SCHEMBL31154524 | 0.71 | ALOX5 (0.55) | CHATPTGS1PTGS2TTRALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2162518-A1 | LUBRICANT COMPOSITIONS STABILIZED WITH STYRENATED PHENOLIC ANTIOXIDANT | CHEMTURA CORPORATION (US) | 2010-03-17 | — | — | EP | disclosed |
| WO-2009009293-A1 | LUBRICANT COMPOSITIONS STABILIZED WITH STYRENATED PHENOLIC ANTIOXIDANT | CHEMTURA CORPORATION (US) | 2009-01-15 | — | — | WO | disclosed |