Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | HNF4A | P41235 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8416884 | 0.87 | TRPA1 (0.53) | TTRALOX5PTGS1PTGS2TRPA1 | |
| SCHEMBL17097110 | 0.87 | TRPA1 (0.53) | TTRALOX5PTGS1PTGS2TRPA1 | |
| SCHEMBL9495620 | 0.83 | TUBB1 (0.59) | TRPA1MAPTNFE2L2TUBB1KDM4E | |
| SCHEMBL3669755 | 0.83 | CHAT (0.44) | TTRALOX5PTGS1PTGS2TRPA1 | |
| SCHEMBL17097111 | 0.82 | TTR (0.53) | TTRALOX5PTGS1PTGS2TRPA1 | |
| SCHEMBL20488356 | 0.81 | ALOX5 (0.56) | TTRALOX5PTGS1PTGS2TRPA1 | |
| SCHEMBL31154524 | 0.79 | ALOX5 (0.55) | TTRALOX5PTGS1PTGS2TRPA1 | |
| SCHEMBL18109192 | 0.79 | TRPA1 (0.52) | TTRALOX5PTGS1PTGS2TRPA1 | |
| SCHEMBL1425963 | 0.79 | TTR (0.63) | TTRALOX5PTGS1PTGS2TRPA1 | |
| SCHEMBL1425965 | 0.79 | TTR (0.63) | TTRALOX5PTGS1PTGS2TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347835-B1 | PROCESS FOR PREPARING ARYL-ETHYL PHENOLS HAVING ONE OR MORE ALKYL SUBSTITUENTS IN THE ETHYL GROUP AND THEIR USE | HIMONT ITALIA S.r.l. (IT) | 1993-04-28 | — | — | EP | disclosed |
| US-5041692-A | Reacting phenol with vinyl group substituted vinyl aromatic hydrocarbon | HIMONT ITALIA S.R.L. (IT) | 1991-08-20 | — | — | US | disclosed |
| EP-0347835-A2 | Process for preparing aryl-ethyl phenols having one or more alkyl substituents in the ethyl group and their use | HIMONT ITALIA S.r.l. (IT) | 1989-12-27 | — | — | EP | disclosed |