Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL1130601 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL22616503 | 0.81 | SIGMAR1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL22616864 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL22616437 | 0.79 | HTR2C (0.31) | — | |
| Hydrochloric Acid SCHEMBL5409609 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL7547921 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL22616724 | 0.78 | HTR2C (0.30) | — | |
| Hydrochloric Acid SCHEMBL5600554 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL5601008 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL31317947 | 0.75 | OXTR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294565-B1 | METALLOCENE-PRODUCED VERY LOW DENSITY POLYETHYLENE AND LOW DENSITY POLYETHYLENE BLENDS | UNIVATION TECH LLC (US) | 2010-03-17 | — | — | EP | disclosed |
| EP-1373404-B1 | POLYETHYLENE BLENDS | UNIVATION TECH LLC (US) | 2009-06-03 | — | — | EP | disclosed |
| EP-1299470-B1 | VERY LOW DENSITY POLYETHYLENE AND HIGH DENSITY POLYETHYLENE BLENDS | UNIVATION TECH LLC (US) | 2007-08-08 | — | — | EP | disclosed |
| EP-1810992-A1 | Polyethylene blends | Univation Technologies, LLC (US) | 2007-07-25 | — | — | EP | disclosed |
| US-7220801-B2 | Metallocene-produced very low density polyethylenes or linear low density polyethylenes as impact modifiers | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-05-22 | — | — | US | disclosed |
| EP-1325073-B1 | METALLOCENE-PRODUCED VERY LOW DENSITY POLYETHYLENES | EXXONMOBIL CHEM PATENTS INC (US) | 2007-05-09 | — | — | EP | disclosed |
| US-20060276594-A1 | Very low density polyethylene blends | UNIVATION TECHNOLOGIES, LLC (US) | 2006-12-07 | — | — | US | disclosed |
| US-7135526-B2 | Very low density polyethylene and high density polyethylene blends | UNIVATION TECHNOLOGIES, LLC (US) | 2006-11-14 | — | — | US | disclosed |
| US-7125933-B2 | Very low density polyethylene blends | UNIVATION TECHNOLOGIES, LLC (US) | 2006-10-24 | — | — | US | disclosed |
| EP-1629018-A1 | CLASS OF METALLOCENES AND METHOD OF PRODUCING POLYETHYLENE | Univation Technologies LLC (US) | 2006-03-01 | — | — | EP | disclosed |
| EP-1373404-A2 | POLYETHYLENE BLENDS | ExxonMobil Chemical Patents Inc. (US) | 2004-01-02 | — | — | EP | disclosed |
| US-20030213938-A1 | Metallocene-produced very low density polyethylenes | EXXONMOBIL CHEMICAL PATENTS INC. | 2003-11-20 | — | — | US | disclosed |
| US-20030215659-A1 | Metallocene-produced very low density polyethylenes | UNIVATION TECHNOLOGIES, LLC | 2003-11-20 | — | — | US | disclosed |
| EP-1325073-A2 | METALLOCENE-PRODUCED VERY LOW DENSITY POLYETHYLENES | ExxonMobil Chemical Patents Inc. (US) | 2003-07-09 | — | — | EP | disclosed |
| EP-1299470-A1 | VERY LOW DENSITY POLYETHYLENE AND HIGH DENSITY POLYETHYLENE BLENDS | ExxonMobil Chemical Patents Inc. (US) | 2003-04-09 | — | — | EP | disclosed |
| EP-1294565-A2 | METALLOCENE-PRODUCED VERY LOW DENSITY POLYETHYLENE AND LOW DENSITY POLYETHYLENE BLENDS | ExxonMobil Chemical Patents Inc. (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002000436-A2 | METALLOCENE-PRODUCED VERY LOW DENSITY POLYETHYLENE AND LOW DENSITY POLYETHYLENE BLENDS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2002-01-03 | — | — | WO | disclosed |
| WO-2001098409-A1 | VERY LOW DENSITY POLYETHYLENE AND HIGH DENSITY POLYETHYLENE BLENDS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2001-12-27 | — | — | WO | disclosed |
| WO-2001098372-A2 | METALLOCENE-PRODUCED VERY LOW DENSITY POLYETHYLENES | EXXONMOBIL CHEMICAL PATENTS, INC. (US) | 2001-12-27 | — | — | WO | disclosed |
| WO-2001098406-A2 | POLYETHYLENE BLENDS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2001-12-27 | — | — | WO | disclosed |