Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8343456 | 0.82 | CYP11B1 (0.36) | CYP19A1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL3670080 | 0.82 | DRD2 (0.33) | CYP19A1CYP11B1CYP11B2 | |
| Fluoride Ion SCHEMBL1130604 | 0.79 | DRD2 (0.33) | — | |
| Hydrochloric Acid SCHEMBL7546508 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL5601820 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL5600559 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL5601013 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL6066625 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL8770753 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL28732822 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798306-B1 | Substituted indenyl unbridged metallocenes | PHILLIPS PETROLEUM CO (US) | 2002-05-22 | — | — | EP | claimed |