Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 8/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.45 |
| ▸ | CCNE2 | O96020 | 4/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.45 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.45 |
| ▸ | CDK1 | P06493 | 8/20 | 0.44 |
| ▸ | CDK9 | P50750 | 3/20 | 0.41 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | CCNT2 | O60583 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE1A | P54750 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3146233 | 0.80 | XDH (0.46) | CDK2CCNA2CCNE2CCNE1CCNA1 | |
| SCHEMBL3137209 | 0.79 | YTHDC1 (0.57) | CDK2CCNE1CDK1ADORA2AYTHDC1 | |
| SCHEMBL3140417 | 0.77 | PDE4A (0.57) | CDK2CCNE1CDK1YTHDC1PDE5A | |
| SCHEMBL3137544 | 0.77 | CDK2 (0.53) | CDK2CCNA2CCNE2CCNE1CCNA1 | |
| SCHEMBL3670288 | 0.76 | PDE4A (0.51) | CDK2CCNE1CDK1YTHDC1PDE5A | |
| SCHEMBL3130740 | 0.75 | CDK2 (0.56) | CDK2CCNA2CCNE2CCNE1CCNA1 | |
| SCHEMBL3145548 | 0.75 | PDE4A (0.41) | CDK2CCNE1CDK1ADORA2AYTHDC1 | |
| SCHEMBL3132183 | 0.75 | CDK2 (0.48) | CDK2CCNA2CCNE2CCNE1CCNA1 | |
| SCHEMBL3146103 | 0.75 | YTHDC1 (0.40) | CDK1YTHDC1PDE5APDE4APDE1A | |
| SCHEMBL3142223 | 0.73 | CRHR1 (0.44) | CDK2CCNE1CDK1ADORA2APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100010020-A1 | PHOSPHODIESTERASE 4 INHIBITORS | LIU RUIPING | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100010020-A1 | PHOSPHODIESTERASE 4 INHIBITORS | PDE4A, PDE3B, PDE3A | CDK2 853/4885CCNA2 2945/4885CCNE2 2815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.