Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367563 | 0.86 | KDM4E (0.52) | MEN1KMT2AMAPTKDM4EPABPC1 | |
| SCHEMBL365590 | 0.85 | KDM4E (0.51) | MEN1KMT2AMAPTKDM4EPABPC1 | |
| SCHEMBL366309 | 0.83 | KDM4E (0.55) | MEN1KMT2AMAPTKDM4EPABPC1 | |
| SCHEMBL365543 | 0.83 | REN (0.53) | MEN1KMT2AMAPTKDM4EPABPC1 | |
| SCHEMBL1144600 | 0.80 | ALDH1A1 (0.51) | MEN1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL367056 | 0.79 | KDM4E (0.41) | MEN1KMT2AMAPTKDM4EPABPC1 | |
| SCHEMBL365013 | 0.77 | KDM4E (0.58) | MEN1KMT2AMAPTKDM4EPABPC1 | |
| SCHEMBL364593 | 0.76 | KMT2A (0.56) | MEN1KMT2AMAPTKDM4EPABPC1 | |
| SCHEMBL365564 | 0.76 | KMT2A (0.56) | MEN1KMT2AMAPTKDM4EPABPC1 | |
| SCHEMBL1144332 | 0.75 | REN (0.65) | MEN1KMT2AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |