Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367563 | 0.90 | KDM4E (0.52) | KDM4EALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL365590 | 0.88 | KDM4E (0.51) | KDM4EALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL365543 | 0.86 | REN (0.53) | KDM4EALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL367057 | 0.83 | MEN1 (0.46) | KDM4EALDH1A1HPGDMAPTL3MBTL1 | |
| SCHEMBL366310 | 0.81 | ALDH1A1 (0.52) | KDM4EALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL365334 | 0.81 | L3MBTL1 (0.47) | ALDH1A1HPGDHSD17B10L3MBTL1RAB9A | |
| SCHEMBL365013 | 0.80 | KDM4E (0.58) | KDM4EALDH1A1HPGDMAPTL3MBTL1 | |
| SCHEMBL365667 | 0.80 | EPHX1 (0.56) | KDM4EALDH1A1HSD17B10L3MBTL1RAB9A | |
| SCHEMBL364593 | 0.79 | KMT2A (0.56) | KDM4EALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL365564 | 0.79 | KMT2A (0.56) | KDM4EALDH1A1HPGDMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |