Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.36 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367059 | 1.00 | KDM4E (0.46) | KDM4EALDH1A1MAPTLMNAHPGD | |
| SCHEMBL366837 | 0.89 | ALDH1A1 (0.40) | KDM4EALDH1A1MAPTLMNAHPGD | |
| SCHEMBL364979 | 0.86 | KDM4E (0.40) | KDM4EALDH1A1MAPTLMNAHPGD | |
| SCHEMBL364978 | 0.86 | KDM4E (0.40) | KDM4EALDH1A1MAPTLMNAHPGD | |
| SCHEMBL367061 | 0.82 | KDM4E (0.43) | KDM4EALDH1A1MAPTLMNAHPGD | |
| SCHEMBL364304 | 0.79 | CHRM1 (0.38) | KDM4EALDH1A1MAPTLMNAHPGD | |
| SCHEMBL366185 | 0.77 | CYP1A2 (0.42) | KDM4EALDH1A1MAPTLMNAHPGD | |
| SCHEMBL365937 | 0.77 | S1PR3 (0.38) | KDM4EALDH1A1MAPTLMNAHPGD | |
| SCHEMBL365936 | 0.77 | S1PR3 (0.38) | KDM4EALDH1A1MAPTLMNAHPGD | |
| SCHEMBL366441 | 0.75 | ALDH1A1 (0.43) | KDM4EALDH1A1MAPTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |