Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.34 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | POLR1A | O95602 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365937 | 1.00 | S1PR3 (0.38) | S1PR3KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL364978 | 0.92 | KDM4E (0.40) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL364979 | 0.92 | KDM4E (0.40) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL366193 | 0.89 | ALDH1A1 (0.36) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL365938 | 0.85 | S1PR3 (0.34) | S1PR3KDM4EALDH1A1NAMPTHPGD | |
| SCHEMBL364304 | 0.78 | CHRM1 (0.38) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL367059 | 0.77 | KDM4E (0.46) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL367060 | 0.77 | KDM4E (0.46) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL364980 | 0.76 | KDM4E (0.37) | KDM4EALDH1A1MAPTNAMPTHPGD | |
| SCHEMBL366194 | 0.75 | CNR1 (0.35) | KDM4EALDH1A1KMT2ANAMPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |