Sugi Predict

Sugi Predict / Compounds / SCHEMBL3671147

SCHEMBL3671147

SCHEMBL3671147

Cc1c(N)cc(Cl)cc1N

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 9/20 0.52
▸ TSHR P16473 5/20 0.50
▸ TP53 P04637 2/20 0.50
▸ CD44 P16070 1/20 0.50
▸ GAA P10253 3/20 0.47
▸ ALDH1A1 P00352 5/20 0.46
▸ ALOX15 P16050 2/20 0.46
▸ SMN1; SMN2 Q16637 2/20 0.46
▸ TDP1 Q9NUW8 1/20 0.46
▸ PIK3CA P42336 1/20 0.43
▸ HPGD P15428 1/20 0.40
▸ ALOX12 P18054 1/20 0.40
▸ MAPK1 P28482 1/20 0.40
▸ HSD17B10 Q99714 1/20 0.40
▸ KMT2A Q03164 1/20 0.39
▸ NPC1 O15118 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8335117 0.92 CYP3A4 (0.46) CYP3A4TSHRTP53CD44GAA
SCHEMBL11229241 0.86 CYP3A4 (0.52) CYP3A4TSHRTP53CD44GAA
SCHEMBL17295667 0.82 CYP3A4 (0.43) CYP3A4TSHRTP53CD44GAA
SCHEMBL3834395 0.82 ALDH1A1 (0.48) CYP3A4TSHRTP53CD44GAA
SCHEMBL10144170 0.82 CYP3A4 (0.43) CYP3A4TSHRTP53CD44GAA
SCHEMBL1494549 0.82 CYP3A4 (0.43) CYP3A4TSHRTP53CD44GAA
SCHEMBL1466729 0.82 CYP3A4 (0.43) CYP3A4TSHRTP53CD44GAA
SCHEMBL3668929 0.82 ALDH1A1 (0.43) CYP3A4TSHRTP53CD44GAA
SCHEMBL6405781 0.78 GABRA1 (0.50) CYP3A4TSHRTP53CD44GAA
SCHEMBL19785965 0.78 CYP3A4 (0.40) CYP3A4TSHRTP53CD44ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109867764-B High removal rate chemical mechanical polishing pad from curing agents containing amine-initiated polyols 罗门哈斯电子材料CMP控股股份有限公司 2021-11-23 — — CN claimed
EP-0153628-A1 Process for producing polyurethane compositions having low hysteresis AIR PRODUCTS AND CHEMICALS, INC. (US) 1985-09-04 — — EP claimed
EP-0153629-A1 A process for producing reinforced polyurethane tires LIM INTERNATIONAL S.A. (LU) 1985-09-04 — — EP claimed
US-4519432-A LOW HYSTERESIS LIM INTERNATIONAL S.A. (LU) 1985-05-28 — — US claimed
US-4507459-A AROMATIC DIAMINE CHAIN EXTENDER, TIRES AIR PRODUCTS AND CHEMICALS, INC. (US) 1985-03-26 — — US claimed
CN-114770369-B Formulation for chemical mechanical polishing pad with high planarization efficiency and CMP pad made therefrom 罗门哈斯电子材料CMP控股股份有限公司 2024-12-10 — — CN disclosed
CN-114770370-B Formulation for high porosity chemical mechanical polishing pad with high hardness and CMP pad made therefrom 罗门哈斯电子材料CMP控股股份有限公司 2024-11-22 — — CN disclosed
CN-114450127-B Polishing pad employing polyamine and cyclohexanedimethanol curing agent CMC材料有限责任公司 2024-05-28 — — CN disclosed
CN-117207058-A CMP pad having low specific gravity polishing layer 罗门哈斯电子材料CMP控股股份有限公司 2023-12-12 — — CN disclosed
CN-117161964-A CMP pad with super-expanded polymer microspheres 罗门哈斯电子材料CMP控股股份有限公司 2023-12-05 — — CN disclosed
CN-117161963-A Method of manufacturing low specific gravity polishing pad 罗门哈斯电子材料CMP控股股份有限公司 2023-12-05 — — CN disclosed
US-11760762-B2 Thienopyranones and furanopyranones as kinase, bromodomain, and checkpoint inhibitors SIGNALRX PHARMACEUTICALS, INC. (US) 2023-09-19 — — US disclosed
CN-85108271-A Make the preparation method of the polyurethane of linking agent with mono-tertiary-alkylated toluenediamine — 1987-02-18 — — CN disclosed
US-4549007-A REACTION INJECTION MOLDING OF POLYURETHANES-POLYUREAS GAF CORPORATION (US) 1985-10-22 — — US disclosed
US-4523004-A 1,4-BUTANEDIOL AND MONOSUBSTITUTED TOLUENE DIAMINE GAF CORPORATION (US) 1985-06-11 — — US disclosed
US-4507459-A AROMATIC DIAMINE CHAIN EXTENDER, TIRES AIR PRODUCTS AND CHEMICALS, INC. (US) 1985-03-26 — — US disclosed
EP-0057871-B1 PROCESS FOR THE PREPARATION OF OPTIONALLY P-CHLORO-SUBSTITUTED 2,6-DIAMINO TOLUENE BAYER AG (DE) 1984-10-03 — — EP disclosed
EP-0102203-A1 Diamine/diol chain extender blends for RIM process GAF CORPORATION (US) 1984-03-07 — — EP disclosed
US-4426538-A Process for the preparation of optionally p-chlorine-substituted 2,6-diaminotoluene BAYER AKTIENGESELLSCHAFT (DE) 1984-01-17 — — US disclosed
EP-0057871-A2 Process for the preparation of optionally p-chloro-substituted 2,6-diamino toluene BAYER AG (DE) 1982-08-18 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11760762-B2 Thienopyranones and furanopyranones as kinase, bromodomain, and checkpoint inhibitors CDK1, CDKN1A, CDKL1 CYP3A4 2479/4885TSHR 2452/4885TP53 138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.