SCHEMBL3671186

SCHEMBL3671186

CCOC(=O)C(C)CSCCSCC(C)C(=O)OCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 8/20 0.43
METAP1 P53582 6/20 0.43
ALDH1A1 P00352 3/20 0.39
CYP3A4 P08684 2/20 0.38
CYP2C19 P33261 2/20 0.38
HSD17B10 Q99714 2/20 0.37
LMNA P02545 1/20 0.37
GAA P10253 2/20 0.37
ALOX15 P16050 2/20 0.36
MGAM O43451 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
SOAT1 P35610 1/20 0.36
CHRM1 P11229 1/20 0.35
ADORA1 P30542 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
HTT P42858 1/20 0.34
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31065468 0.91 METAP2 (0.42) METAP2METAP1ALDH1A1CYP3A4CYP2C19
SCHEMBL12934328 0.87 METAP2 (0.40) METAP2METAP1ALDH1A1CYP3A4CYP2C19
SCHEMBL31135395 0.85 CES2 (0.46) METAP2METAP1HSD17B10CYP2C9POLB
SCHEMBL16626926 0.82 ALDH1A1 (0.42) METAP2METAP1ALDH1A1CYP3A4CYP2C19
SCHEMBL12707543 0.82 ALDH1A1 (0.42) METAP2METAP1ALDH1A1CYP3A4CYP2C19
SCHEMBL12707546 0.82 ALDH1A1 (0.42) METAP2METAP1ALDH1A1CYP3A4CYP2C19
SCHEMBL7025313 0.82 CYP2C19 (0.51) ALDH1A1CYP3A4CYP2C19HSD17B10LMNA
SCHEMBL9874566 0.82 ALDH1A1 (0.38) METAP2METAP1ALDH1A1CYP3A4CYP2C19
SCHEMBL16215319 0.78 ALDH1A1 (0.39) METAP2METAP1ALDH1A1CYP3A4CYP2C19
SCHEMBL18113296 0.77 ALDH1A1 (0.37) METAP2METAP1ALDH1A1CYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7714087-B2 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS, INC. (JP) 2010-05-11 US disclosed
US-20090137757-A1 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof IMUTA JUNICHI 2009-05-28 US disclosed
US-7393907-B2 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS, INC. (JP) 2008-07-01 US disclosed
EP-1734061-A2 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer and uses thereof MITSUI CHEMICALS, INC. (JP) 2006-12-20 EP disclosed
EP-1186619-B1 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition contaning the copolymer, and uses thereof MITSUI CHEMICALS INC (JP) 2006-11-29 EP disclosed
EP-1044989-B1 Method for preparing polymer MITSUI CHEMICALS INC (JP) 2005-06-22 EP disclosed
US-6762259-B2 ACCURATE MOLECULAR WEIGHT CONTROL; POLYMERIZATION OF POLAR UNSATURATED MONOMERS IN PRESENCE OF HYDROXYCARBONYL COMPOUND AND ORGANIC OXYSALT CATALYST MITSUI CHEMICALS, INC. (JP) 2004-07-13 US disclosed
US-20040122192-A1 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS, INC. 2004-06-24 US disclosed
US-6528599-B1 Polar unsaturated compound; anionic polymerization MITSUI CHEMICALS, INC. (JP) 2003-03-04 US disclosed
US-20030023003-A1 Process for the production of living (co)polymers and use of the (co)polymers MITSUI CHEMICALS, INC. (JP) 2003-01-30 US disclosed
EP-1266910-A1 PROCESS FOR THE PRODUCTION OF LIVING (CO)POLYMERS AND USE OF THE (CO)POLYMERS Mitsui Chemicals, Inc. (JP) 2002-12-18 EP disclosed
US-20020156207-A1 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS, INC. (JP) 2002-10-24 US disclosed
EP-1186619-A2 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition contaning the copolymer, and uses thereof Mitsui Chemicals, Inc. (JP) 2002-03-13 EP disclosed
EP-1044989-A1 Method for preparing polymer Mitsui Chemicals, Inc. (JP) 2000-10-18 EP disclosed