Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL539076 | 0.86 | PIN1 (0.51) | PIN1MMP8POLBALDH1A1RECQL | |
| SCHEMBL31455095 | 0.85 | CYP1A2 (0.49) | PIN1MMP8ALDH1A1RECQLMAPT | |
| SCHEMBL27564031 | 0.85 | PIN1 (0.50) | PIN1MMP8POLBALDH1A1RECQL | |
| Hydrochloric Acid SCHEMBL17825610 | 0.84 | MAPT (0.43) | NPSR1MAPTKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL27846451 | 0.83 | PIN1 (0.49) | PIN1MMP8POLBALDH1A1RECQL | |
| SCHEMBL28084453 | 0.83 | PIN1 (0.49) | PIN1MMP8POLBALDH1A1RECQL | |
| SCHEMBL19797979 | 0.83 | KCNN4 (0.46) | PIN1POLBALDH1A1NPSR1MAPT | |
| SCHEMBL17825617 | 0.83 | KCNN4 (0.56) | TAAR1ALDH1A1RECQLCHRM2CHRM4 | |
| SCHEMBL21656355 | 0.82 | KDM4E (0.46) | POLBALDH1A1NPSR1MAPTKMT2A | |
| SCHEMBL14510428 | 0.81 | PIN1 (0.50) | PIN1MMP8TAAR1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3850022-A1 | COMPOSITE MATERIALS INCLUDING CERAMIC FIBERS AND NANOCLUSTERS, DENTAL PRODUCTS, KITS, AND METHODS OF MAKING AND USING SAME | 3M Innovative Properties Company (US) | 2021-07-21 | — | — | EP | disclosed |
| WO-2020053723-A1 | COMPOSITE MATERIALS INCLUDING CERAMIC FIBERS AND NANOCLUSTERS, DENTAL PRODUCTS, KITS, AND METHODS OF MAKING AND USING SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2020-03-19 | — | — | WO | disclosed |
| CN-104470895-B | The purposes of N [3 (2 carboxy ethyl) phenyl] piperidinyl-1 yl acetamide derivatives and its activator as soluble guanylate cyclase | 拜耳制药股份公司 | 2017-04-05 | — | — | CN | disclosed |
| EP-2139892-A1 | SUBSTITUTED PYRIMIDODIAZEPINES USEFUL AS PLK1 INHIBITORS | F. Hoffmann-Roche AG (CH) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008113711-A1 | SUBSTITUTED PYRIMIDODIAZEPINES USEFUL AS PLK1 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-09-25 | — | — | WO | disclosed |
| US-20070112199-A1 | Asymmetric aldol additions using bifunctional cinchona-alkaloid-based catalysts | BRANDEIS UNIVERSITY (US) | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112199-A1 | Asymmetric aldol additions using bifunctional cinchona-alkaloid-based catalysts | AKR1C2, AKR1A1, AKR1B1 | PIN1 362/4885MMP8 2537/4885TAAR1 2165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.