Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | BID | P55957 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28321854 | 0.86 | GABRA1 (0.56) | LIPGALOX5PTGS2GABRA1GABRB2 | |
| SCHEMBL31075131 | 0.84 | LIPG (0.55) | LIPGALOX5PTGS2GABRA1GABRB2 | |
| SCHEMBL6679786 | 0.81 | LIPG (0.44) | LIPGALOX5PTGS2GABRA1GABRB2 | |
| SCHEMBL4763408 | 0.81 | BID (0.47) | LIPGALOX5PTGS2TLR8BID | |
| SCHEMBL981336 | 0.80 | LIPG (0.55) | LIPGALOX5PTGS2TLR8BID | |
| SCHEMBL28748793 | 0.79 | BID (0.50) | LIPGALOX5PTGS2TLR8BID | |
| SCHEMBL10824471 | 0.79 | CYP3A4 (0.48) | LIPGALOX5PTGS2TLR8BID | |
| SCHEMBL9163528 | 0.79 | BID (0.50) | LIPGALOX5PTGS2TLR8BID | |
| SCHEMBL9166810 | 0.79 | BID (0.50) | LIPGALOX5PTGS2TLR8BID | |
| SCHEMBL8088586 | 0.79 | BID (0.50) | LIPGALOX5PTGS2TLR8BID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966223-B1 | CATALYST COMPOSITION COMPRISING GROUP 4 TRANSITION METAL COMPLEXES AND METHOD FOR PREPARING POLYOLEFINS USING THE SAME | LG CHEMICAL LTD (KR) | 2013-08-14 | — | — | EP | disclosed |
| US-7807762-B2 | Catalyst composition comprising Group 4 transition metal complexes and method for preparing polyolefins using the same | LG CHEM, LTD. (KR) | 2010-10-05 | — | — | US | disclosed |
| US-20090005525-A1 | Catalyst Composition Comprising Group 4 Transition Metal Complexes and Method for Preparing Polyolefins Using the Same | LG CHEM , LTD. (KR) | 2009-01-01 | — | — | US | disclosed |
| EP-1966223-A1 | CATALYST COMPOSITION COMPRISING GROUP 4 TRANSITION METAL COMPLEXES AND METHOD FOR PREPARING POLYOLEFINS USING THE SAME | LG Chem. Ltd. (KR) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007078133-A1 | CATALYST COMPOSITION COMPRISING GROUP 4 TRANSITION METAL COMPLEXES AND METHOD FOR PREPARING POLYOLEFINS USING THE SAME | LG CHEM. LTD. (KR) | 2007-07-12 | — | — | WO | disclosed |