Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.55 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | BID | P55957 | 3/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.42 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL983151 | 0.98 | LIPG (0.58) | LIPGTLR8CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL932540 | 0.98 | LIPG (0.58) | LIPGTLR8CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2230507 | 0.98 | LIPG (0.58) | LIPGTLR8CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL634079 | 0.98 | LIPG (0.58) | LIPGTLR8CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL985061 | 0.98 | LIPG (0.58) | LIPGTLR8CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4069404 | 0.98 | LIPG (0.58) | LIPGTLR8CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4431698 | 0.98 | LIPG (0.58) | LIPGTLR8CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL177297 | 0.98 | LIPG (0.58) | LIPGTLR8CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL984903 | 0.98 | LIPG (0.58) | LIPGTLR8CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL634069 | 0.98 | LIPG (0.58) | LIPGTLR8CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 270 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114276286-A | Method for preparing N, N-disubstituted-alpha, beta-unsaturated enamine from arone and secondary nitrogen compound | 长沙资材科技有限公司 | 2022-04-05 | — | — | CN | claimed |
| EP-3368643-A2 | LUBRICATING OIL COMPOSITIONS CONTAINING AMIDINE ANTIOXIDANTS | Chevron Oronite Company LLC (US) | 2018-09-05 | — | — | EP | claimed |
| US-20170121625-A1 | LUBRICATING OIL COMPOSITIONS CONTAINING AMIDINE ANTIOXIDANTS | CHEVRON ORONITE COMPANY LLC | 2017-05-04 | — | — | US | claimed |
| US-20100004454-A1 | QUINOLINIUM ION DERIVATIVES, PROCESS FOR THE PRODUCTION OF THE DERIVATIVES, PRODUCTS MADE BY USING THE SAME, AND REDUCTION AND OXIDATION METHODS WITH THE DERIVATIVES | OSAKA UNIVERSITY (JP) | 2010-01-07 | — | — | US | claimed |
| EP-1797163-A2 | METHOD FOR REDUCING THE FREEZING POINT OF AMINATED AVIATION GASOLINE BY THE USE OF TERTIARYAMYLPHENYLAMINE | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2007-06-20 | — | — | EP | claimed |
| WO-2006026657-A2 | METHOD FOR REDUCING THE FREEZING POINT OF AMINATED AVIATION GASOLINE BY THE USE OF TERTIARYAMYLPHENYLAMINE | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2006-03-09 | — | — | WO | claimed |
| EP-1528062-A2 | Process for the preparation of s-type 4-substituted hydroxypyranoindolidine compounds | TANABE SEIYAKU CO., LTD. (JP) | 2005-05-04 | — | — | EP | claimed |
| US-20030135049-A1 | S type 2-substituted hydroxy-2-indolidinylbutyric ester compounds and process for preparation thereof | TANABE SEIYAKU CO., LTD. | 2003-07-17 | — | — | US | claimed |
| US-20020161231-A1 | Stype 2-substituted hydroxy-2-indolidinylbutyric ester compounds and process for preparation thereof | TANABE SEIYAKU CO., LTD. | 2002-10-31 | — | — | US | claimed |
| EP-1236728-A2 | S-type 2-substituted hydroxy-2-indolinylbutyric ester compounds and process for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 2002-09-04 | — | — | EP | claimed |
| US-6015901-A | INTERMEDIATES FOR ANTITUMOR AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 2000-01-18 | — | — | US | claimed |
| EP-0845464-A2 | S type 2-substituted hydroxy-2-indolidinylbutyric ester compounds as intermediates for camptothecin derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1998-06-03 | — | — | EP | claimed |
| EP-0325247-B1 | CAMPTOTHECIN DERIVATIVES AND PROCESS FOR PREPARING SAME | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1993-05-19 | — | — | EP | claimed |
| EP-0325247-A1 | Camptothecin derivatives and process for preparing same | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1989-07-26 | — | — | EP | claimed |
| EP-0002309-B1 | ACYLANILIDES, PROCESS FOR THEIR MANUFACTURE AND PHARMACEUTICAL AND VETERINARY COMPOSITIONS CONTAINING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-12-01 | — | — | EP | claimed |
| JP-1186892-A | — | — | None | — | — | JP | disclosed |
| JP-57200337-A | — | — | None | — | — | JP | disclosed |
| JP-S57200337-A | NOVEL 2-ACYLANILINE DERIVATIVE | ISHIKAWA MASAYUKI | 1982-12-08 | — | — | JP | disclosed |
| US-4046554-A | HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1977-09-06 | — | — | US | disclosed |
| US-3966811-A | HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020161231-A1 | Stype 2-substituted hydroxy-2-indolidinylbutyric ester compounds and process for preparation thereof | TOP2B, TOP2A, SI | LIPG 4206/4885TLR8 1480/4885CYP1A2 304/4885 |
| US-20030135049-A1 | S type 2-substituted hydroxy-2-indolidinylbutyric ester compounds and process for preparation thereof | TOP2B, TOP2A, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | LIPG 3770/4885TLR8 2581/4885CYP1A2 150/4885 |
| US-20100004454-A1 | QUINOLINIUM ION DERIVATIVES, PROCESS FOR THE PRODUCTION OF THE DERIVATIVES, PRODUCTS MADE BY USING THE SAME, AND REDUCTION AND OXIDATION METHODS WITH THE DERIVATIVES | APEX1, NQO1, POT1 | LIPG 4317/4885TLR8 4312/4885CYP1A2 2589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.