Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.69 |
| ▸ | MMP2 | P08253 | 1/20 | 0.63 |
| ▸ | MMP7 | P09237 | 1/20 | 0.63 |
| ▸ | MMP14 | P50281 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6554003 | 0.98 | NPC1 (0.67) | NPC1MMP2MMP7MMP14ALDH1A1 | |
| SCHEMBL6554026 | 0.98 | NPC1 (0.67) | NPC1MMP2MMP7MMP14ALDH1A1 | |
| Guanidine SCHEMBL2289728 | 0.91 | NPC1 (0.69) | NPC1MMP2MMP7MMP14ALDH1A1 | |
| SCHEMBL7017091 | 0.82 | MMP2 (0.49) | NPC1MMP2MMP7MMP14ALDH1A1 | |
| SCHEMBL7401928 | 0.82 | NPC1 (1.00) | NPC1ALDH1A1KDM4EHSD11B1CYP3A4 | |
| SCHEMBL6554020 | 0.82 | NPC1 (0.67) | NPC1MMP2MMP7MMP14ALDH1A1 | |
| SCHEMBL2027971 | 0.82 | NPC1 (0.67) | NPC1ALDH1A1KDM4EHSD11B1CYP3A4 | |
| SCHEMBL6554000 | 0.82 | NPC1 (0.67) | NPC1MMP2MMP7MMP14ALDH1A1 | |
| SCHEMBL1981537 | 0.81 | MMP2 (0.66) | MMP2MMP7MMP14HSD11B1 | |
| SCHEMBL270706 | 0.80 | MMP2 (0.77) | MMP2MMP7MMP14ALDH1A1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1046496-B1 | Planographic printing plate precursor containing metal compounds, and process for producing planographic printing plates | FUJI PHOTO FILM CO LTD (JP) | 2004-02-18 | — | — | EP | claimed |
| US-11905361-B2 | Base proliferating agent, and base-reactive resin composition containing said base proliferating agent | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2024-02-20 | — | — | US | disclosed |
| EP-3998260-B1 | SGC STIMULATORS | CYCLERION THERAPEUTICS INC (US) | 2023-11-01 | — | — | EP | disclosed |
| CN-109369635-B | Compound or pharmaceutically acceptable salt thereof, application thereof and pharmaceutical composition | 赛克里翁治疗有限公司 | 2023-06-30 | — | — | CN | disclosed |
| US-20230106002-A1 | sGC STIMULATORS | IRONWOOD PHARMACEUTICALS, INC. | 2023-04-06 | — | — | US | disclosed |
| CN-109384778-B | Use of a compound or a pharmaceutically acceptable salt thereof for the manufacture of a medicament for the treatment of a disease, health condition or disorder | 赛克里翁治疗有限公司 | 2022-12-13 | — | — | CN | disclosed |
| US-20220332886-A1 | Base Proliferating Agent, and Base-Reactive Resin Composition Containing Said Base Proliferating Agent | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2022-10-20 | — | — | US | disclosed |
| US-11401370-B2 | Base proliferating agent, and base-reactive resin composition containing said base proliferating agent | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2022-08-02 | — | — | US | disclosed |
| CN-110016020-B | Compound or pharmaceutically acceptable salt thereof, application and pharmaceutical composition thereof | 赛克里翁治疗有限公司 | 2022-07-26 | — | — | CN | disclosed |
| EP-3998260-A1 | SGC STIMULATORS | Cyclerion Therapeutics, Inc. (US) | 2022-05-18 | — | — | EP | disclosed |
| EP-0383358-A2 | Light-sensitive material containing silver halide reducing agent and polymerizable compound | FUJI PHOTO FILM CO., LTD. (JP) | 1990-08-22 | — | — | EP | disclosed |
| US-4933367-A | Carboxylic acid derivatives, processes for the preparation thereof, the use thereof, and pharmaceutical compositions which contain these compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1990-06-12 | — | — | US | disclosed |
| US-4897335-A | Light-sensitive material containing silver halide, reducing agent polymerizable compound, and base arranged outside of microcapsules | FUJI PHOTO FILM CO., LTD. (JP) | 1990-01-30 | — | — | US | disclosed |
| US-4705737-A | Heat developable photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1987-11-10 | — | — | US | disclosed |
| EP-0237058-A2 | Light sensitive material containing silver halide, reducing agent and polymerizable compound | FUJI PHOTO FILM CO., LTD. (JP) | 1987-09-16 | — | — | EP | disclosed |
| EP-0120403-B1 | HEAT DEVELOPABLE COLOR PHOTOGRAPHIC MATERIALS | FUJI PHOTO FILM CO., LTD. (JP) | 1987-06-10 | — | — | EP | disclosed |
| US-4514493-A | STORAGE STABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 1985-04-30 | — | — | US | disclosed |
| EP-0120403-A2 | Heat developable color photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1984-10-03 | — | — | EP | disclosed |
| EP-0027895-A1 | 1-(2-(Alkyl and arylsulfonyl)-2-propenyl and propyl) substituted piperidines and pharmaceutical and antimicrobial compositions comprising the same | MERCK & CO. INC. (US) | 1981-05-06 | — | — | EP | disclosed |
| US-4244963-A | 1-[2-(Alkyl and arylsulfonyl)-2-propenyl and propyl] substituted piperidines useful as antimicrobial and antiinflammatory agents | MERCK & CO., INC. (US) | 1981-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230106002-A1 | sGC STIMULATORS | PTGIS, CGAS, GUCY1A1 | NPC1 2841/4885MMP2 3522/4885MMP7 4312/4885 |
| US-11905361-B2 | Base proliferating agent, and base-reactive resin composition containing said base proliferating agent | PCNA, MKI67, POLR1A | NPC1 3376/4885MMP2 3678/4885MMP7 4022/4885 |
| US-11401370-B2 | Base proliferating agent, and base-reactive resin composition containing said base proliferating agent | PCNA, MKI67, POLR1A | NPC1 3376/4885MMP2 3678/4885MMP7 4022/4885 |
| US-20220332886-A1 | Base Proliferating Agent, and Base-Reactive Resin Composition Containing Said Base Proliferating Agent | PCNA, MKI67, POLR1A | NPC1 3376/4885MMP2 3678/4885MMP7 4022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.