SCHEMBL3671959

SCHEMBL3671959

CC(C)(O)C(=O)c1ccc(COC(=O)CC(=O)OCc2ccc(C(=O)C(C)(C)O)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.44
MAPT P10636 3/20 0.44
KMT2A Q03164 6/20 0.44
MEN1 O00255 3/20 0.43
RAB9A P51151 2/20 0.43
SMN1; SMN2 Q16637 4/20 0.42
HPGD P15428 2/20 0.41
GAA P10253 2/20 0.41
MAPK1 P28482 2/20 0.41
KDM4E B2RXH2 1/20 0.41
NPC1 O15118 1/20 0.41
TSHR P16473 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TP53 P04637 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3677449 0.90 RAB9A (0.45) ALDH1A1MAPTKMT2AMEN1RAB9A
SCHEMBL5568855 0.87 KMT2A (0.41) ALDH1A1MAPTKMT2AMEN1RAB9A
SCHEMBL3668172 0.87 KMT2A (0.41) ALDH1A1MAPTKMT2AMEN1RAB9A
SCHEMBL3670798 0.86 KMT2A (0.40) ALDH1A1MAPTKMT2AMEN1RAB9A
SCHEMBL5569719 0.86 KMT2A (0.40) ALDH1A1MAPTKMT2AMEN1RAB9A
SCHEMBL3677676 0.85 ALDH1A1 (0.43) ALDH1A1MAPTKMT2AMEN1RAB9A
SCHEMBL3676951 0.85 ALDH1A1 (0.55) ALDH1A1MAPTKMT2AMEN1SMN1; SMN2
SCHEMBL3670930 0.85 KMT2A (0.62) ALDH1A1MAPTKMT2AMEN1RAB9A
SCHEMBL3673108 0.83 KMT2A (0.38) ALDH1A1MAPTKMT2AMEN1RAB9A
SCHEMBL278995 0.82 ALDH1A1 (0.46) ALDH1A1MAPTKMT2AMEN1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7642296-B2 2-hydroxy-1-(4-hydroxymethyl-phenyl)-2-methyl-propan-1-one, have higher reactivity at the benzylic hydroxy group and do not have a tendency to yellowing; photocurable composition for pigmented or non-pigmented varnish surface coatings CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-01-05 US disclosed
US-20070240609-A1 Photoinitiators IGM GROUP B.V. (NL) 2007-10-18 US disclosed
EP-1763499-B1 NEW PHOTOINITIATORS CIBA SC HOLDING AG (CH) 2007-09-26 EP disclosed
EP-1763499-A1 NEW PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) 2007-03-21 EP disclosed
WO-2005100292-A1 NEW PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-10-27 WO disclosed