SCHEMBL3670798

SCHEMBL3670798

CCCC(=O)OCc1ccc(C(=O)C(C)(C)O)cc1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.40
MEN1 O00255 1/20 0.40
RAB9A P51151 2/20 0.40
ALDH1A1 P00352 5/20 0.39
MAPT P10636 3/20 0.39
HSD17B3 P37058 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
CA2 P00918 1/20 0.37
MAPK1 P28482 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
GAA P10253 1/20 0.36
PKM P14618 1/20 0.36
CYP4F2 P78329 1/20 0.36
CYP4A11 Q02928 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3677449 0.92 RAB9A (0.45) KMT2AMEN1RAB9AALDH1A1MAPT
SCHEMBL3668172 0.89 KMT2A (0.41) KMT2AMEN1RAB9AALDH1A1MAPT
SCHEMBL3673376 0.89 DGKA (0.45) HSD17B3
SCHEMBL5569719 0.88 KMT2A (0.40) KMT2AMEN1RAB9AALDH1A1MAPT
SCHEMBL3671959 0.86 ALDH1A1 (0.44) KMT2AMEN1RAB9AALDH1A1MAPT
SCHEMBL5568855 0.83 KMT2A (0.41) KMT2AMEN1RAB9AALDH1A1MAPT
SCHEMBL3670930 0.81 KMT2A (0.62) KMT2AMEN1RAB9AALDH1A1MAPT
SCHEMBL3676951 0.81 ALDH1A1 (0.55) KMT2AMEN1ALDH1A1MAPTSMN1; SMN2
SCHEMBL27861194 0.80 KMT2A (0.43) KMT2AMEN1RAB9AALDH1A1MAPT
SCHEMBL3673108 0.79 KMT2A (0.38) KMT2AMEN1RAB9AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7642296-B2 2-hydroxy-1-(4-hydroxymethyl-phenyl)-2-methyl-propan-1-one, have higher reactivity at the benzylic hydroxy group and do not have a tendency to yellowing; photocurable composition for pigmented or non-pigmented varnish surface coatings CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-01-05 US disclosed
CN-100548955-C photoinitiator CIBA SC HOLDING AG (CH) 2009-10-14 CN disclosed
US-20070240609-A1 Photoinitiators IGM GROUP B.V. (NL) 2007-10-18 US disclosed
EP-1763499-B1 NEW PHOTOINITIATORS CIBA SC HOLDING AG (CH) 2007-09-26 EP disclosed
CN-1942424-A Novel photoinitiators CIBA SC HOLDING AG (CH) 2007-04-04 CN disclosed
EP-1763499-A1 NEW PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) 2007-03-21 EP disclosed
WO-2005100292-A1 NEW PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-10-27 WO disclosed