Hydrochloric Acid

Hydrochloric Acid

SCHEMBL3672116

CC1=CC(C)([Zr+2]C2=CC=CC2)c2ccccc21.[Cl-].[Cl-]

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
CYP3A4 P08684 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
HPGD P15428 1/20 0.32
KMT2A Q03164 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
APOBEC3A P31941 1/20 0.31
APOBEC3G Q9HC16 1/20 0.31
PGR P06401 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3681014 0.75
Hydrochloric Acid SCHEMBL3670079 0.73
Hydrochloric Acid SCHEMBL18663207 0.71
Hydrochloric Acid SCHEMBL3677452 0.70
SCHEMBL5597349 0.70 ALDH1A1 (0.33) ALDH1A1CYP3A4HSD17B10TDP1KDM4E
Hydrochloric Acid SCHEMBL7549574 0.70
Fluoride Ion SCHEMBL1130601 0.70
Hydrochloric Acid SCHEMBL22616724 0.70 HTR2C (0.30)
Hydrochloric Acid SCHEMBL2354743 0.69
Hydrochloric Acid SCHEMBL3672122 0.69 ALDH1A1 (0.34) ALDH1A1CYP3A4HSD17B10TDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1294565-B1 METALLOCENE-PRODUCED VERY LOW DENSITY POLYETHYLENE AND LOW DENSITY POLYETHYLENE BLENDS UNIVATION TECH LLC (US) 2010-03-17 EP disclosed
EP-1373404-B1 POLYETHYLENE BLENDS UNIVATION TECH LLC (US) 2009-06-03 EP disclosed
EP-1299470-B1 VERY LOW DENSITY POLYETHYLENE AND HIGH DENSITY POLYETHYLENE BLENDS UNIVATION TECH LLC (US) 2007-08-08 EP disclosed
EP-1810992-A1 Polyethylene blends Univation Technologies, LLC (US) 2007-07-25 EP disclosed
US-7220801-B2 Metallocene-produced very low density polyethylenes or linear low density polyethylenes as impact modifiers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-05-22 US disclosed
US-20060276594-A1 Very low density polyethylene blends UNIVATION TECHNOLOGIES, LLC (US) 2006-12-07 US disclosed
US-7135526-B2 Very low density polyethylene and high density polyethylene blends UNIVATION TECHNOLOGIES, LLC (US) 2006-11-14 US disclosed
US-7125933-B2 Very low density polyethylene blends UNIVATION TECHNOLOGIES, LLC (US) 2006-10-24 US disclosed
EP-1629018-A1 CLASS OF METALLOCENES AND METHOD OF PRODUCING POLYETHYLENE Univation Technologies LLC (US) 2006-03-01 EP disclosed
US-6953828-B2 Polymeric membrane compositions EXXONMOBIL CHEMICAL PATENTS, INC. (US) 2005-10-11 US disclosed
US-20040072005-A1 Suitable in blown and cast film applications UNIVATION TECHNOLOGIES, LLC 2004-04-15 US disclosed
US-20040014895-A1 Very low density polyethylene and high density polyethylene blends UNIVATION TECHNOLOGIES, LLC 2004-01-22 US disclosed
EP-1373404-A2 POLYETHYLENE BLENDS ExxonMobil Chemical Patents Inc. (US) 2004-01-02 EP disclosed
US-20030213938-A1 Metallocene-produced very low density polyethylenes EXXONMOBIL CHEMICAL PATENTS INC. 2003-11-20 US disclosed
US-20030215659-A1 Metallocene-produced very low density polyethylenes UNIVATION TECHNOLOGIES, LLC 2003-11-20 US disclosed
WO-2003033585-A1 POLYMERIC MEMBRANE COMPOSITIONS EXXONMOBILE CHEMICAL PATENTS INC. (US) 2003-04-24 WO disclosed
EP-1294565-A2 METALLOCENE-PRODUCED VERY LOW DENSITY POLYETHYLENE AND LOW DENSITY POLYETHYLENE BLENDS ExxonMobil Chemical Patents Inc. (US) 2003-03-26 EP disclosed
WO-2003000790-A1 METALLOCENE-PRODUCED VERY LOW DENSITY POLYETHYLENES OR LINEAR LOWDENSITY POLYETHYLENES AS IMPACT MODIFIERS EXXONMOBIL CHEMICAL PATENTS, INC. (US) 2003-01-03 WO disclosed
WO-2002000436-A2 METALLOCENE-PRODUCED VERY LOW DENSITY POLYETHYLENE AND LOW DENSITY POLYETHYLENE BLENDS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-01-03 WO disclosed
WO-2001098406-A2 POLYETHYLENE BLENDS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2001-12-27 WO disclosed