SCHEMBL3672551

SCHEMBL3672551

CC(C)(C)c1cc(CSCCO)cc(C(C)(C)C)c1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.51
MAPT P10636 5/20 0.51
KDM4E B2RXH2 5/20 0.51
TSHR P16473 4/20 0.51
MAPK1 P28482 3/20 0.51
LMNA P02545 3/20 0.51
CYP1A2 P05177 3/20 0.51
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
GSR P00390 2/20 0.51
HPGD P15428 2/20 0.51
CYP3A4 P08684 2/20 0.51
BLM P54132 2/20 0.51
ATM Q13315 2/20 0.51
HIF1A Q16665 2/20 0.51
NPSR1 Q6W5P4 2/20 0.51
ALOX15 P16050 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
CYP2C9 P11712 2/20 0.51
GMNN O75496 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9507166 0.91 ALDH1A1 (0.53) ALDH1A1MAPTKDM4ETSHRMAPK1
SCHEMBL1275496 0.90 HSPA5 (0.49) ALDH1A1MAPTKDM4ETSHRMAPK1
SCHEMBL38964 0.87 ALDH1A1 (0.57) ALDH1A1MAPTKDM4ETSHRMAPK1
Hydrogen Sulfide SCHEMBL28290635 0.85 ALDH1A1 (0.55) ALDH1A1MAPTKDM4ETSHRMAPK1
SCHEMBL20356825 0.84 PTGS2 (0.48) ALDH1A1MAPTKDM4ETSHRMAPK1
SCHEMBL582925 0.83 ALDH1A1 (0.46) ALDH1A1MAPTKDM4ETSHRMAPK1
SCHEMBL11808205 0.81 ALDH1A1 (0.47) ALDH1A1MAPTKDM4ETSHRMAPK1
SCHEMBL10684907 0.80 ALDH1A1 (0.46) ALDH1A1MAPTKDM4ETSHRMAPK1
SCHEMBL9576103 0.80 ALDH1A1 (0.46) ALDH1A1MAPTKDM4ETSHRMAPK1
SCHEMBL10776996 0.80 ALDH1A1 (0.51) ALDH1A1MAPTKDM4ETSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7807757-B2 stabilizing and at the same time phase compatibilizing plastics or plastic compositions by incorporating maleic anhydride or acrylic acid grafted copolymer or terpolymer (styrene/butadiene/styrene block copolymer grafted with maleic anhydride) obtained by reacting with a benzotriazole compound CIBA SPECIALTY CHEMICALS CORP. (US) 2010-10-05 US disclosed
US-20080051521-A1 Functionalized polymers PFAENDNER RUDOLF 2008-02-28 US disclosed
US-7300978-B2 Functionalised polymers CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-11-27 US disclosed
US-20040167291-A1 Functionalised polymers PFAENDNER RUDOLF (DE) 2004-08-26 US disclosed
US-20020123577-A1 Functionalised polymers PFAENDNER RUDOLF (DE) 2002-09-05 US disclosed
US-6362278-B1 STABILIZATION USING STERIC HINDERED AMINE COMPOUND CIBA SPECIALTY CHEMICALS CORPORATION 2002-03-26 US disclosed
EP-0935619-B1 FUNCTIONALISED POLYMERS CIBA SC HOLDING AG (CH) 2001-06-20 EP disclosed
EP-0935619-A1 FUNCTIONALISED POLYMERS Ciba SC Holding AG (CH) 1999-08-18 EP disclosed
WO-1998018830-A1 FUNCTIONALISED POLYMERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-05-07 WO disclosed