Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3676817 | 0.86 | ALDH1A1 (0.33) | DHFRALDH1A1CYP1A2ALOX15CASP7 | |
| SCHEMBL3673769 | 0.79 | ALDH1A1 (0.39) | GABRA1GABRB2ALDH1A1CYP1A2ALOX15 | |
| SCHEMBL11008908 | 0.79 | HTT (0.42) | GABRA1GABRB2DHFRALDH1A1CYP1A2 | |
| SCHEMBL16556091 | 0.79 | HTT (0.38) | GABRA1GABRB2DHFRALDH1A1CYP1A2 | |
| SCHEMBL3678945 | 0.78 | DHFR (0.36) | DHFRPOLBHTTSMN1; SMN2 | |
| SCHEMBL3675789 | 0.78 | DHFR (0.36) | DHFRCYP1A2HIF1APOLBHTT | |
| SCHEMBL395350 | 0.77 | HTT (0.41) | GABRA1GABRB2DHFRALDH1A1POLB | |
| SCHEMBL3676615 | 0.76 | ALDH1A1 (0.32) | ALDH1A1CYP1A2ALOX15CASP7HIF1A | |
| SCHEMBL3679070 | 0.73 | SKP2 (0.40) | GABRA1GABRB2ALDH1A1CYP1A2ALOX15 | |
| SCHEMBL393744 | 0.73 | HTT (0.43) | GABRA1GABRB2DHFRALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1426392-B1 | COMPOSITION FOR OPTICAL MATERIAL | MITSUBISHI GAS CHEMICAL CO (JP) | 2010-02-24 | — | — | EP | disclosed |
| US-6960640-B2 | Composition for optical material | MITSUBISHI GAS CHEMICAL CO., LTD. (JP) | 2005-11-01 | — | — | US | disclosed |
| US-20040147708-A1 | Composition for optical material | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2004-07-29 | — | — | US | disclosed |
| EP-1426392-A1 | COMPOSITION FOR OPTICAL MATERIAL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2004-06-09 | — | — | EP | disclosed |