Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8153959 | 0.80 | HTT (0.42) | HTTPOLBALDH1A1MAPTNOS3 | |
| SCHEMBL12797845 | 0.80 | HTT (0.42) | HTTPOLBALDH1A1MAPTNOS3 | |
| SCHEMBL3672623 | 0.79 | GABRA1 (0.37) | HTTPOLBGABRA1GABRB2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4771781 | 0.78 | HTT (0.41) | HTTPOLBALDH1A1MAPTNOS3 | |
| SCHEMBL10431866 | 0.77 | ALDH1A1 (0.41) | HTTPOLBALDH1A1CYP1A2ALOX15 | |
| SCHEMBL27593883 | 0.76 | HTT (0.42) | HTTPOLBALDH1A1MAPTNOS3 | |
| SCHEMBL9799254 | 0.76 | POLB (0.38) | HTTPOLBALDH1A1MAPTNOS3 | |
| SCHEMBL16556091 | 0.75 | HTT (0.38) | HTTPOLBGABRA1GABRB2ALDH1A1 | |
| SCHEMBL11147869 | 0.73 | ALDH1A1 (0.42) | HTTPOLBGABRA1GABRB2ALDH1A1 | |
| SCHEMBL394710 | 0.73 | NOS3 (0.39) | HTTPOLBGABRA1GABRB2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0135017-A1 | Process for the stabilisation of poly(phenylene ether) solutions | BASF Aktiengesellschaft (DE) | 1985-03-27 | — | — | EP | disclosed |