Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.37 |
| ▸ | CHRNG | P07510 | 2/20 | 0.37 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | CHRND | Q07001 | 2/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 6/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 6/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3669530 | 0.87 | CHRNA1 (0.37) | GRM1MEN1CYP1A2KMT2ATDP1 | |
| SCHEMBL7640361 | 0.78 | SMN1; SMN2 (0.50) | MEN1KMT2ATDP1TAS1R3TAS1R1 | |
| SCHEMBL12250617 | 0.77 | GRM1 (0.49) | GRM1MEN1CYP1A2KMT2ATDP1 | |
| SCHEMBL3738996 | 0.75 | CES2 (0.35) | GRM1MEN1CYP1A2KMT2ATDP1 | |
| SCHEMBL2502807 | 0.75 | CA1 (0.49) | GRM1MEN1CYP1A2KMT2ATDP1 | |
| SCHEMBL537689 | 0.73 | PTPN5 (0.38) | CES2CES1CA2 | |
| SCHEMBL10940962 | 0.72 | TDP1 (0.41) | TDP1HTTSMN1; SMN2CA2RXRA | |
| SCHEMBL3677108 | 0.72 | ELANE (0.33) | TAS1R3TAS1R1CA2 | |
| SCHEMBL8436007 | 0.71 | PDE2A (0.40) | GRM1MEN1CYP1A2KMT2ATDP1 | |
| SCHEMBL3669475 | 0.71 | ACE2 (0.43) | CES2CES1HTTSMN1; SMN2RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642296-B2 | 2-hydroxy-1-(4-hydroxymethyl-phenyl)-2-methyl-propan-1-one, have higher reactivity at the benzylic hydroxy group and do not have a tendency to yellowing; photocurable composition for pigmented or non-pigmented varnish surface coatings | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-01-05 | — | — | US | disclosed |
| US-20070240609-A1 | Photoinitiators | IGM GROUP B.V. (NL) | 2007-10-18 | — | — | US | disclosed |
| EP-1763499-B1 | NEW PHOTOINITIATORS | CIBA SC HOLDING AG (CH) | 2007-09-26 | — | — | EP | disclosed |
| EP-1763499-A1 | NEW PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2007-03-21 | — | — | EP | disclosed |
| WO-2005100292-A1 | NEW PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-10-27 | — | — | WO | disclosed |