Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.34 |
| ▸ | USP5 | P45974 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3671849 | 0.86 | CA2 (0.37) | MLYCDALDH1A1CYP2C9CYP2D6HIF1A | |
| SCHEMBL4197514 | 0.86 | ESR1 (0.43) | MLYCDALDH1A1CYP2C9CYP2D6HIF1A | |
| SCHEMBL480335 | 0.86 | ELANE (0.47) | MLYCDALDH1A1CYP2C9CYP2D6HIF1A | |
| SCHEMBL54909 | 0.86 | CYP2C9 (0.50) | ALDH1A1CYP2C9CYP2D6HIF1AUSP5 | |
| SCHEMBL3667690 | 0.85 | HDAC1 (0.37) | MLYCDALDH1A1CYP2C9CYP2D6HIF1A | |
| SCHEMBL11298330 | 0.82 | CA2 (0.46) | MLYCDALDH1A1CA2HDAC1TSHR | |
| SCHEMBL13457935 | 0.82 | HDAC1 (0.38) | MLYCDALDH1A1CYP2C9CYP2D6HIF1A | |
| SCHEMBL29061558 | 0.82 | ALDH1A1 (0.36) | MLYCDALDH1A1CYP2C9CYP2D6HIF1A | |
| SCHEMBL10942936 | 0.81 | CYP2C9 (0.46) | ALDH1A1CYP2C9CYP2D6HIF1AUSP5 | |
| SCHEMBL8957565 | 0.81 | KIF11 (0.46) | PTPN5ALDH1A1CYP2C9CYP2D6HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2766750-B1 | METHOD FOR MAKING UV-ABSORBING OPHTHALMIC LENSES BY COATING | NOVARTIS AG (CH) | 2016-02-03 | — | — | EP | disclosed |
| US-9005700-B2 | Method for making UV-absorbing ophthalmic lenses | NOVARTIS AG (CH) | 2015-04-14 | — | — | US | disclosed |
| EP-2766750-A1 | METHOD FOR MAKING UV-ABSORBING OPHTHALMIC LENSES BY COATING | Novartis AG (CH) | 2014-08-20 | — | — | EP | disclosed |
| US-8703875-B2 | Polymers | NOVARTIS AG (CH) | 2014-04-22 | — | — | US | disclosed |
| US-8647699-B2 | Method for coating silicone hydrogels | NOVARTIS AG (CH) | 2014-02-11 | — | — | US | disclosed |
| US-8609745-B2 | Production of ophthalmic devices based on photo-induced step growth polymerization | NOVARTIS AG (CH) | 2013-12-17 | — | — | US | disclosed |
| US-20130172600-A1 | Novel Polymers | NOVARTIS AG (CH) | 2013-07-04 | — | — | US | disclosed |
| US-20130106007-A1 | PRODUCTION OF OPHTHALMIC DEVICES BASED ON PHOTO-INDUCED STEP GROWTH POLYMERIZATION | NOVARTIS AG (CH) | 2013-05-02 | — | — | US | disclosed |
| US-20130095235-A1 | METHOD FOR MAKING UV-ABSORBING OPHTHALMIC LENSES | NOVARTIS AG (CH) | 2013-04-18 | — | — | US | disclosed |
| WO-2013055746-A1 | METHOD FOR MAKING UV-ABSORBING OPHTHALMIC LENSES BY COATING | NOVARTIS AG (CH) | 2013-04-18 | — | — | WO | disclosed |
| US-20090186229-A1 | Method for coating silicone hydrogels | ALCON INC. (CH) | 2009-07-23 | — | — | US | disclosed |
| EP-0953613-B1 | Ink, ink-jet recording method using the same, and photopolymerization initiator | CANON KK (JP) | 2009-07-08 | — | — | EP | disclosed |
| EP-2038310-A2 | ACTINICALLY CROSSLINKABLE COPOLYMERS FOR MANUFACTURING CONTACT LENSES | Novartis AG (CH) | 2009-03-25 | — | — | EP | disclosed |
| US-20090029413-A1 | Process for the manufacture of a composite material | ALCON INC. (CH) | 2009-01-29 | — | — | US | disclosed |
| WO-2008107448-A2 | PROCESS FOR THE MANUFACTURE OF A COMPOSITE MATERIAL | NOVARTIS AG (CH) | 2008-09-12 | — | — | WO | disclosed |
| WO-2008076729-A1 | PRODUCTION OF OPHTHALMIC DEVICES BASED ON PHOTO-INDUCED STEP GROWTH POLYMERIZATION | NOVARTIS AG (CH) | 2008-06-26 | — | — | WO | disclosed |
| US-20080152800-A1 | Process for the coating of biomedical articles | ALCON INC. (CH) | 2008-06-26 | — | — | US | disclosed |
| US-20080143958-A1 | Production of ophthalmic devices based on photo-induced step growth polymerization | ALCON INC. (CH) | 2008-06-19 | — | — | US | disclosed |
| WO-2008008752-A2 | ACTINICALLY CROSSLINKABLE COPOLYMERS FOR MANUFACTURING CONTACT LENSES | NOVARTIS AG (CH) | 2008-01-17 | — | — | WO | disclosed |
| US-20080015315-A1 | Novel Polymers | ALCON INC. (CH) | 2008-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172600-A1 | Novel Polymers | PAM, MTHFD2, PCNA | PTPN5 4413/4885MLYCD 1356/4885ALDH1A1 71/4885 |
| US-20090029413-A1 | Process for the manufacture of a composite material | ECPAS, C1QBP, PLOD3 | PTPN5 2827/4885MLYCD 4631/4885ALDH1A1 961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.