Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 5/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | VDR | P11473 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18075239 | 0.74 | PDE2A (0.68) | PDE2A | |
| SCHEMBL30481795 | 0.74 | PDE2A (0.68) | PDE2A | |
| SCHEMBL8436415 | 0.73 | HCAR3 (0.39) | CYP2D6CYP2C9HIF1ACYP1A2MEN1 | |
| SCHEMBL8432092 | 0.73 | ESR1 (0.46) | CYP2D6CYP2C9HIF1ACYP1A2TDP1 | |
| SCHEMBL9156166 | 0.71 | TDP1 (0.48) | CYP2D6CYP2C9HIF1ACYP1A2TDP1 | |
| SCHEMBL25374759 | 0.71 | PDE2A (0.50) | PDE2AAR | |
| SCHEMBL3673147 | 0.71 | GRM1 (0.41) | PDE2ACYP1A2GRM1TDP1MEN1 | |
| SCHEMBL8434483 | 0.70 | VDR (0.49) | MEN1KMT2AALDH1A1VDRAR | |
| SCHEMBL30271542 | 0.69 | TRPA1 (0.50) | PDE2ACYP1A2TDP1ALDH1A1 | |
| SCHEMBL19205698 | 0.69 | TRPA1 (0.50) | PDE2ACYP1A2TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0605404-B1 | Polycyclic dyes | BASF AG (DE) | 1999-12-08 | — | — | EP | disclosed |
| EP-0363034-B1 | Polycyclic dyes | ZENECA LTD (GB) | 1995-01-04 | — | — | EP | disclosed |
| US-5212313-A | For polyester | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-05-18 | — | — | US | disclosed |
| US-5183888-A | Reacting a phenyl tartronic acid with a dihydrobenzofuran, oxidizing, to get dihydrobenzodifuran | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-02 | — | — | US | disclosed |
| US-5084580-A | Aniline dyes for polyester fabrics to give green and blue color | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-28 | — | — | US | disclosed |
| EP-0363034-A2 | Polycyclic dyes | ZENECA LIMITED (GB) | 1990-04-11 | — | — | EP | disclosed |