Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3677950 | 0.84 | MEN1 (0.51) | MAPTALDH1A1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL9508340 | 0.83 | MAOA (0.35) | L3MBTL1 | |
| SCHEMBL3684146 | 0.78 | SRD5A2 (0.47) | HPGDL3MBTL1 | |
| SCHEMBL3791542 | 0.75 | CYP3A4 (0.46) | MAPTALDH1A1L3MBTL1 | |
| SCHEMBL3676453 | 0.74 | NQO1 (0.47) | MAPTALDH1A1NQO1SMN1; SMN2HPGD | |
| SCHEMBL2488793 | 0.73 | NQO1 (0.74) | MAPTALDH1A1NQO1SMN1; SMN2HPGD | |
| Ammonia Solution, Strong SCHEMBL27962960 | 0.73 | MAOA (0.47) | SMN1; SMN2 | |
| Ethylene SCHEMBL28271283 | 0.71 | MAOA (0.46) | SMN1; SMN2 | |
| SCHEMBL18973131 | 0.71 | HAO1 (0.38) | MAPTALDH1A1LMNAHTTGAA | |
| SCHEMBL18973135 | 0.71 | MAPT (0.40) | MAPTALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825188-B2 | Thermoplastic elastomer with acyloxyphenyl hard block segment | DESIGNER MOLECULES, INC. (US) | 2010-11-02 | — | — | US | claimed |
| WO-2008077141-A1 | RUBBER EPOXY CURATIVES AND METHODS FOR USE THEREOF | DESIGNER MOLECULES, INC. (US) | 2008-06-26 | — | — | WO | claimed |
| US-20080146738-A1 | RUBBER EPOXY CURATIVES AND METHODS FOR USE THEREOF | DESIGNER MOLECULES, INC. | 2008-06-19 | — | — | US | claimed |
| US-7825188-B2 | Thermoplastic elastomer with acyloxyphenyl hard block segment | DESIGNER MOLECULES, INC. (US) | 2010-11-02 | — | — | US | disclosed |
| WO-2008077141-A1 | RUBBER EPOXY CURATIVES AND METHODS FOR USE THEREOF | DESIGNER MOLECULES, INC. (US) | 2008-06-26 | — | — | WO | disclosed |
| US-20080146738-A1 | RUBBER EPOXY CURATIVES AND METHODS FOR USE THEREOF | DESIGNER MOLECULES, INC. | 2008-06-19 | — | — | US | disclosed |