Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | CPT2 | P23786 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10298961 | 0.80 | CYP2C19 (0.35) | CYP2C19HIF1AHMGCRCHRM1TBXA2R | |
| SCHEMBL10298937 | 0.79 | CYP2C19 (0.34) | CYP2C19HIF1AHMGCRCHRM1TBXA2R | |
| SCHEMBL7023519 | 0.77 | CYP2C19 (0.33) | CYP2C19HIF1AHMGCRCHRM1TBXA2R | |
| SCHEMBL10298936 | 0.77 | CYP2C19 (0.33) | CYP2C19HIF1AHMGCRCHRM1TBXA2R | |
| SCHEMBL7020215 | 0.77 | CYP2C19 (0.33) | CYP2C19HIF1AHMGCRCHRM1TBXA2R | |
| SCHEMBL13937723 | 0.76 | HMGCR (0.41) | CYP2C19HIF1AHMGCRCHRM1TBXA2R | |
| SCHEMBL7024357 | 0.73 | HMGCR (0.38) | CYP2C19HIF1AHMGCRCHRM1TBXA2R | |
| SCHEMBL16884889 | 0.72 | — | — | |
| SCHEMBL7026051 | 0.70 | CYP2C19 (0.36) | CYP2C19HIF1AHMGCRCHRM1TBXA2R | |
| SCHEMBL7022374 | 0.70 | MALT1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120171229-A1 | SYNTHETIC NANOCARRIERS WITH REACTIVE GROUPS THAT RELEASE BIOLOGICALLY ACTIVE AGENTS | SELECTA BIOSCIENCES, INC. (US) | 2012-07-05 | — | — | US | disclosed |
| US-20120171229-A1 | SYNTHETIC NANOCARRIERS WITH REACTIVE GROUPS THAT RELEASE BIOLOGICALLY ACTIVE AGENTS | SELECTA BIOSCIENCES, INC. (US) | 2012-07-05 | — | — | US | disclosed |
| US-7807402-B2 | Reagent for fluorimetric determination of analytes | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2010-10-05 | — | — | US | disclosed |
| US-20080305469-A1 | Fluorimetric Determination of Analytes By An Intramolecular Quencher-Fluorophore Conjugate | ROCHE DIAGNOSTICS GMBH (DE) | 2008-12-11 | — | — | US | disclosed |
| US-7378255-B2 | Fluorimetric determination of analytes by an intramolecular quencher-fluorophore conjugate | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2008-05-27 | — | — | US | disclosed |
| US-20040234945-A1 | Fluorimetric determination of analytes by an intramolecular quencher-fluorophore conjugate | ROCHE DIAGNOSTICS GMBH (DE) | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120171229-A1 | SYNTHETIC NANOCARRIERS WITH REACTIVE GROUPS THAT RELEASE BIOLOGICALLY ACTIVE AGENTS | HAVCR2, IFNG, MAVS | CYP2C19 4155/4885HIF1A 1861/4885HMGCR 1299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.