SCHEMBL3673937

SCHEMBL3673937

O=C(/C=C/c1ccc(OCc2ccccc2)c(OCc2ccccc2)c1)c1c(O)cc(OCc2ccccc2)cc1OCc1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC5A1 P13866 1/20 0.66
▸ SLC5A2 P31639 1/20 0.66
▸ KDM4E B2RXH2 3/20 0.60
▸ LMNA P02545 2/20 0.60
▸ PDE4A P27815 1/20 0.60
▸ PDE4B Q07343 1/20 0.60
▸ PDE4C Q08493 1/20 0.60
▸ PDE4D Q08499 1/20 0.60
▸ ALDH1A1 P00352 2/20 0.59
▸ THRB P10828 1/20 0.59
▸ ABCG2 Q9UNQ0 2/20 0.55
▸ APP P05067 4/20 0.54
▸ CYP3A4 P08684 3/20 0.53
▸ MAPT P10636 3/20 0.53
▸ KMT2A Q03164 3/20 0.53
▸ TP53 P04637 2/20 0.53
▸ ATM Q13315 1/20 0.53
▸ HSD17B10 Q99714 1/20 0.53
▸ AKR1C3 P42330 1/20 0.53
▸ MEN1 O00255 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25223332 1.00 SLC5A1 (0.66) SLC5A1SLC5A2KDM4ELMNAPDE4A
SCHEMBL31233231 1.00 SLC5A1 (0.66) SLC5A1SLC5A2KDM4ELMNAPDE4A
SCHEMBL30382807 1.00 SLC5A1 (0.66) SLC5A1SLC5A2KDM4ELMNAPDE4A
SCHEMBL30383521 1.00 SLC5A1 (0.66) SLC5A1SLC5A2KDM4ELMNAPDE4A
SCHEMBL25207126 0.92 SLC5A1 (0.65) SLC5A1SLC5A2KDM4ELMNAPDE4A
SCHEMBL25196269 0.91 PDE4A (0.58) SLC5A1SLC5A2KDM4ELMNAPDE4A
SCHEMBL30383937 0.91 PDE4A (0.58) SLC5A1SLC5A2KDM4ELMNAPDE4A
SCHEMBL25196754 0.91 PDE4A (0.58) SLC5A1SLC5A2KDM4ELMNAPDE4A
SCHEMBL30383214 0.91 PDE4A (0.58) SLC5A1SLC5A2KDM4ELMNAPDE4A
SCHEMBL13657210 0.91 SLC5A1 (0.80) SLC5A1SLC5A2KDM4EPDE4APDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
US-20100048920-A1 Preparation of (+)-Catechin, (-)-Epicatechin, (-)-Catechin, and (+)-Epicatechin and Their 5,7,3',4'-Tetra-O-Benzyl Analogues MARS, INCORPORATED (US) 2010-02-25 — — US disclosed
US-20100048920-A1 Preparation of (+)-Catechin, (-)-Epicatechin, (-)-Catechin, and (+)-Epicatechin and Their 5,7,3',4'-Tetra-O-Benzyl Analogues MARS, INCORPORATED (US) 2010-02-25 — — US disclosed
EP-1896443-A1 PREPARATION OF (+)-CATECHIN, (-)-EPICATECHIN, (-)-CATECHIN, (+)-EPICATECHIN, AND THEIR 5,7,3',4'-TETRA-O-BENZYL ANALOGUES MARS, INCORPORATED (US) 2008-03-12 — — EP disclosed
WO-2007002877-A1 PREPARATION OF (+)-CATECHIN, (-)-EPICATECHIN, (-)-CATECHIN, (+)-EPICATECHIN, AND THEIR 5,7,3',4'-TETRA-O-BENZYL ANALOGUES MARS, INCORPORATED (US) 2007-01-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B SLC5A1 3752/4885SLC5A2 4208/4885KDM4E 1732/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 SLC5A1 4485/4885SLC5A2 4756/4885KDM4E 2652/4885
US-20100048920-A1 Preparation of (+)-Catechin, (-)-Epicatechin, (-)-Catechin, and (+)-Epicatechin and Their 5,7,3',4'-Tetra-O-Benzyl Analogues HAAO, TES, HPD SLC5A1 1758/4885SLC5A2 2594/4885KDM4E 263/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 SLC5A1 4485/4885SLC5A2 4756/4885KDM4E 2652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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