SCHEMBL25207126

SCHEMBL25207126

O=C(C=Cc1ccc(OCc2ccccc2)c(-c2cc(C=CC(=O)c3c(O)cc(OCc4ccccc4)cc3OCc3ccccc3)ccc2OCc2ccccc2)c1)c1c(O)cc(OCc2ccccc2)cc1OCc1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC5A1 P13866 1/20 0.65
▸ SLC5A2 P31639 1/20 0.65
▸ PDE4A P27815 1/20 0.56
▸ PDE4B Q07343 1/20 0.56
▸ PDE4C Q08493 1/20 0.56
▸ PDE4D Q08499 1/20 0.56
▸ CYP3A4 P08684 3/20 0.52
▸ MAPT P10636 3/20 0.52
▸ KMT2A Q03164 3/20 0.52
▸ ABCG2 Q9UNQ0 2/20 0.52
▸ TP53 P04637 2/20 0.52
▸ ATM Q13315 1/20 0.52
▸ HSD17B10 Q99714 1/20 0.52
▸ APP P05067 1/20 0.52
▸ KDM4E B2RXH2 4/20 0.51
▸ ALDH1A1 P00352 3/20 0.51
▸ MEN1 O00255 2/20 0.51
▸ HPGD P15428 2/20 0.51
▸ TDP1 Q9NUW8 2/20 0.51
▸ USP2 O75604 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30382807 0.92 SLC5A1 (0.66) SLC5A1SLC5A2PDE4APDE4BPDE4C
SCHEMBL30383521 0.92 SLC5A1 (0.66) SLC5A1SLC5A2PDE4APDE4BPDE4C
SCHEMBL3673937 0.92 SLC5A1 (0.66) SLC5A1SLC5A2PDE4APDE4BPDE4C
SCHEMBL25223332 0.92 SLC5A1 (0.66) SLC5A1SLC5A2PDE4APDE4BPDE4C
SCHEMBL31233231 0.92 SLC5A1 (0.66) SLC5A1SLC5A2PDE4APDE4BPDE4C
SCHEMBL13657210 0.90 SLC5A1 (0.80) SLC5A1SLC5A2PDE4APDE4BPDE4C
SCHEMBL4883627 0.90 SLC5A1 (0.80) SLC5A1SLC5A2PDE4APDE4BPDE4C
SCHEMBL30384339 0.90 SLC5A1 (0.80) SLC5A1SLC5A2PDE4APDE4BPDE4C
SCHEMBL30384783 0.90 SLC5A1 (0.80) SLC5A1SLC5A2PDE4APDE4BPDE4C
SCHEMBL1727986 0.90 SLC5A1 (0.72) SLC5A1SLC5A2PDE4APDE4BPDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B SLC5A1 3752/4885SLC5A2 4208/4885PDE4A 3506/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 SLC5A1 4485/4885SLC5A2 4756/4885PDE4A 3576/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 SLC5A1 4485/4885SLC5A2 4756/4885PDE4A 3576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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