Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | RAB9A | P51151 | 1/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HPGDS | O60760 | 1/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | POLR1A | O95602 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18758196 | 0.88 | RAB9A (0.56) | KMT2ARAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL13211934 | 0.84 | KMT2A (1.00) | KMT2ARAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL11973926 | 0.84 | RAB9A (0.76) | KMT2ARAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL14817956 | 0.84 | KMT2A (0.76) | KMT2ARAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL1402380 | 0.84 | RAB9A (0.76) | KMT2ARAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL18740419 | 0.82 | RAB9A (0.61) | KMT2ARAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL18740416 | 0.82 | RAB9A (0.61) | KMT2ARAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL18758129 | 0.81 | KMT2A (0.60) | KMT2ARAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL10031654 | 0.80 | KMT2A (0.59) | KMT2ARAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL15136263 | 0.80 | KMT2A (0.59) | KMT2ARAB9AKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593437-B1 | MOLECULES HAVING COMBINABLE GROUPS | ARKEMA FRANCE (FR) | 2017-09-06 | — | — | EP | disclosed |
| EP-2593437-B1 | MOLECULES HAVING COMBINABLE GROUPS | ARKEMA FRANCE (FR) | 2017-09-06 | — | — | EP | disclosed |
| WO-2017064296-A1 | METHOD FOR SYNTHESISING AROMATIC NITRONES | ARKEMA FRANCE (FR) | 2017-04-20 | — | — | WO | disclosed |
| US-9045432-B2 | Nitrile oxide, nitrone, and nitrile imine compounds | ARKEMA FRANCE (FR) | 2015-06-02 | — | — | US | disclosed |
| US-9045432-B2 | Nitrile oxide, nitrone, and nitrile imine compounds | ARKEMA FRANCE (FR) | 2015-06-02 | — | — | US | disclosed |
| US-9045432-B2 | Nitrile oxide, nitrone, and nitrile imine compounds | ARKEMA FRANCE (FR) | 2015-06-02 | — | — | US | disclosed |
| US-20130197237-A1 | MOLECULES HAVING COMBINABLE GROUPS | ARKEMA FRANCE (FR) | 2013-08-01 | — | — | US | disclosed |
| US-20130197237-A1 | MOLECULES HAVING COMBINABLE GROUPS | ARKEMA FRANCE (FR) | 2013-08-01 | — | — | US | disclosed |
| US-20130197237-A1 | MOLECULES HAVING COMBINABLE GROUPS | ARKEMA FRANCE (FR) | 2013-08-01 | — | — | US | disclosed |
| EP-2593437-A1 | MOLECULES HAVING COMBINABLE GROUPS | Arkema France (FR) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007684-A1 | MOLECULES HAVING COMBINABLE GROUPS | ARKEMA FRANCE (FR) | 2012-01-19 | — | — | WO | disclosed |
| WO-2012007684-A1 | MOLECULES HAVING COMBINABLE GROUPS | ARKEMA FRANCE (FR) | 2012-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130197237-A1 | MOLECULES HAVING COMBINABLE GROUPS | NCAPH, NCL, PARG | KMT2A 3304/4885RAB9A 2902/4885KDM4E 4089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.