Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 2/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.45 |
| ▸ | TACR1 | P25103 | 2/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | UBE2M | P61081 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3668638 | 0.90 | MTOR (0.64) | MTORCA12CA1CA2CA9 | |
| SCHEMBL3666331 | 0.85 | MTOR (0.47) | MTORMAPTTACR1MGLL | |
| SCHEMBL1948090 | 0.85 | PTGDR2 (0.61) | MTORRAB9A | |
| SCHEMBL3671609 | 0.84 | MLYCD (0.52) | MTORMEN1KMT2AAOC3TACR1 | |
| SCHEMBL3672476 | 0.82 | MTOR (0.43) | MTORAOC3TACR1DCUN1D1UBE2M | |
| SCHEMBL3666874 | 0.82 | ABHD6 (0.54) | MTORMEN1KMT2AAOC3TACR1 | |
| SCHEMBL3666865 | 0.78 | HDAC6 (0.56) | MEN1KMT2ATACR1 | |
| SCHEMBL3674357 | 0.77 | MTOR (0.56) | MTORMAPTTP53TACR1 | |
| SCHEMBL12564544 | 0.76 | PTGDR2 (0.52) | MTORRAB9A | |
| SCHEMBL3667568 | 0.76 | MGLL (0.42) | MEN1KMT2ATACR1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240434-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | Ligand Pharmaceuticals Inc. (US) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009089192-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | LIGAND PHARMACEUTICALS INC. (US) | 2009-07-16 | — | — | WO | disclosed |