SCHEMBL3674357

SCHEMBL3674357

CN(Cc1cc(C(F)(F)F)cc(-c2ccccc2)c1[O])C(=O)Nc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MTOR P42345 2/20 0.56
TACR1 P25103 10/20 0.47
TP53 P04637 1/20 0.43
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3674358 0.89 MTOR (0.56) MTORTACR1TP53MAPT
SCHEMBL3671389 0.83 TACR1 (0.43) MTORTACR1
SCHEMBL3672556 0.83 TACR1 (0.55) TACR1
SCHEMBL3665166 0.80 TACR1 (0.47) TACR1
SCHEMBL3669056 0.77 TACR1 (0.43) TACR1
SCHEMBL3668636 0.77 MTOR (0.64) MTORTACR1TP53MAPT
SCHEMBL3668571 0.76 GPBAR1 (0.52) TACR1
SCHEMBL3668638 0.74 MTOR (0.64) MTORTACR1TP53MAPT
SCHEMBL3671391 0.72 TACR1 (0.43) MTORTACR1
SCHEMBL16518676 0.72 MLYCD (0.63) MTORTACR1TP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2240434-A1 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS Ligand Pharmaceuticals Inc. (US) 2010-10-20 EP claimed
WO-2009089192-A1 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS LIGAND PHARMACEUTICALS INC. (US) 2009-07-16 WO claimed