Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 5/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LAP3 | P28838 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.36 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.36 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.35 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.35 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9234022 | 0.99 | FDPS (0.46) | FDPSSMPD1MEN1MAPTKMT2A | |
| SCHEMBL9000621 | 0.94 | FDPS (0.44) | FDPSSMPD1MEN1MAPTKMT2A | |
| SCHEMBL3675754 | 0.88 | POLB (0.36) | FDPS | |
| SCHEMBL3889930 | 0.85 | MMP8 (0.37) | MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL9380998 | 0.81 | CYP4F2 (0.36) | MEN1KMT2A | |
| SCHEMBL2353089 | 0.78 | MEN1 (0.43) | FDPSSMPD1MEN1MAPTKMT2A | |
| SCHEMBL2349851 | 0.78 | MEN1 (0.43) | FDPSSMPD1MEN1MAPTKMT2A | |
| SCHEMBL2350480 | 0.78 | MEN1 (0.43) | FDPSSMPD1MEN1MAPTKMT2A | |
| SCHEMBL2352898 | 0.78 | MEN1 (0.43) | FDPSSMPD1MEN1MAPTKMT2A | |
| SCHEMBL2357271 | 0.78 | MEN1 (0.43) | FDPSSMPD1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203161-B1 | QUINONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | UNIV INDIANA RES & TECH CORP (US) | 2018-05-09 | — | — | EP | disclosed |
| US-9089605-B2 | Quinone derivatives, pharmaceutical compositions, and uses thereof | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2015-07-28 | — | — | US | disclosed |
| US-20100297113-A1 | QUINONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | PURDUE RESEARCH FOUNDATION | 2010-11-25 | — | — | US | disclosed |
| EP-2203161-A1 | QUINONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | Indiana University Research and Technology Corporation (US) | 2010-07-07 | — | — | EP | disclosed |
| WO-2009042544-A1 | QUINONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2009-04-02 | — | — | WO | disclosed |
| EP-0419905-B1 | Quinone derivatives and pharmacological use | EISAI CO LTD (JP) | 1996-01-17 | — | — | EP | disclosed |
| US-5385942-A | Therapy of cirrhosis, liver disorders | EISAI CO., LTD. (JP) | 1995-01-31 | — | — | US | disclosed |
| US-5210239-A | Treatment of Hepatic Diseases | EISAI CO., LTD. (JP) | 1993-05-11 | — | — | US | disclosed |
| EP-0419905-A2 | Quinone derivatives and pharmacological use | Eisai Co., Ltd. (JP) | 1991-04-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100297113-A1 | QUINONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | APEX1, NQO1, REV1 | FDPS 1009/4885SMPD1 2896/4885MEN1 2751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.