SCHEMBL3674575

SCHEMBL3674575

CCCC[SiH](OC)OC.[CH3]

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
LMNA P02545 1/20 0.33
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL274371 0.97
Ammonia Solution, Strong SCHEMBL28015905 0.94 TSHR (0.33) TSHRLMNATHRB
Methylamine SCHEMBL302747 0.92 ADRB2 (0.33) TSHRLMNATHRB
Dimethylamine SCHEMBL28515102 0.89 EPHX1 (0.31) TSHRLMNA
Ethylamine SCHEMBL9171476 0.89 DNM1 (0.33) TSHRLMNA
SCHEMBL250819 0.88 TSHR (0.39) TSHRLMNATHRB
Ethylenediamine SCHEMBL54975 0.87 DNM1 (0.38) TSHR
SCHEMBL16834811 0.86 TSHR (0.44) TSHRLMNATHRB
SCHEMBL631129 0.86 TSHR (0.44) TSHRLMNATHRB
SCHEMBL6325266 0.86 TSHR (0.44) TSHRLMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100160540-A1 Process for the Nucleation of Polypropylene Resins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2010-06-24 US disclosed