Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | LOX | P28300 | 1/20 | 0.33 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL297924 | 0.77 | — | — | |
| SCHEMBL2227603 | 0.75 | TSHR (0.34) | ALDH1A1TDP1TSHRTHRB | |
| Hydrochloric Acid SCHEMBL5595671 | 0.75 | — | — | |
| SCHEMBL31424303 | 0.73 | TSHR (0.42) | ALDH1A1TDP1TSHRGAATHRB | |
| SCHEMBL5595628 | 0.73 | LMNA (0.42) | ALDH1A1TDP1TSHRGAATHRB | |
| SCHEMBL5146789 | 0.73 | — | — | |
| SCHEMBL13850664 | 0.73 | TSHR (0.37) | ALDH1A1TDP1TSHRGAATHRB | |
| SCHEMBL2225539 | 0.71 | TSHR (0.32) | ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL5595683 | 0.71 | ABCC3 (0.44) | ALDH1A1TDP1TSHRGAATHRB | |
| SCHEMBL11197516 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099845-B1 | MULTI-FUNCTIONAL POLYALKYLENE OXIDES, HYDROGELS AND TISSUE ADHESIVES | ACTAMAX SURGICAL MAT LLC (US) | 2020-12-23 | — | — | EP | disclosed |
| US-8282959-B2 | Branched end reactants and polymeric hydrogel tissue adhesives therefrom | ACTAMAX SURGICAL MATERIALS, LLC (US) | 2012-10-09 | — | — | US | disclosed |
| US-20100086678-A1 | BRANCHED END REACTANTS AND POLYMERIC HYDROGEL TISSUE ADHESIVES THEREFROM | E.I.DUPONT DE NEMOURS AND COMPANY (DE) | 2010-04-08 | — | — | US | disclosed |