SCHEMBL2225539

SCHEMBL2225539

C[Si](C)(C)C(CC#N)NCCC#N

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2227603 0.74 TSHR (0.34) TSHRALDH1A1
SCHEMBL31424303 0.73 TSHR (0.42) TSHRALDH1A1
SCHEMBL3674627 0.71 ALDH1A1 (0.41) TSHRALDH1A1
SCHEMBL11344169 0.68 LMNA (0.38) TSHRALDH1A1
SCHEMBL31472204 0.68 TSHR (0.33) TSHR
SCHEMBL297924 0.67
Hydrochloric Acid SCHEMBL5595671 0.66
SCHEMBL13850664 0.64 TSHR (0.37) TSHRALDH1A1
SCHEMBL5146789 0.64
SCHEMBL5595628 0.64 LMNA (0.42) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011091346-A2 POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP BRIDGESTONE CORPORATION (JP) 2011-07-28 WO disclosed