Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3285305 | 0.78 | MAPK1 (0.37) | CYP3A4 | |
| SCHEMBL8053276 | 0.75 | NOTUM (0.32) | — | |
| SCHEMBL3279947 | 0.57 | LMNA (0.40) | CYP3A4 | |
| SCHEMBL3278058 | 0.57 | MAPK1 (0.39) | CYP3A4 | |
| Pentachlorobenzene SCHEMBL183144 | 0.55 | CYP3A4 (1.00) | CYP3A4 | |
| Pentachlorobenzene SCHEMBL11455164 | 0.55 | CYP3A4 (1.00) | CYP3A4 | |
| SCHEMBL7043130 | 0.55 | RHEB (0.54) | CYP3A4 | |
| SCHEMBL15709305 | 0.54 | CYP3A4 (0.35) | CYP3A4 | |
| SCHEMBL337232 | 0.54 | SLC9A1 (0.56) | CYP3A4 | |
| SCHEMBL29162274 | 0.54 | CYP3A4 (0.39) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150056160-A1 | CHEMICALLY INDUCED INTRACELLULAR HYPERTHERMIA | TEXAS PHARMACEUTICALS, INC. | 2015-02-26 | — | — | US | claimed |
| EP-1098641-A4 | CHEMICALLY INDUCED INTRACELLULAR HYPERTHERMIA | ST JUDE PHARMACEUTICALS INC (US) | 2003-08-27 | — | — | EP | claimed |
| EP-1098641-A1 | CHEMICALLY INDUCED INTRACELLULAR HYPERTHERMIA | Texas Pharmaceuticals, Inc. (US) | 2001-05-16 | — | — | EP | claimed |
| WO-2000006143-A1 | CHEMICALLY INDUCED INTRACELLULAR HYPERTHERMIA | TEXAS PHARMACEUTICALS, INC. (US) | 2000-02-10 | — | — | WO | claimed |
| EP-1098641-B1 | CHEMICALLY INDUCED INTRACELLULAR HYPERTHERMIA | ST JUDE PHARMACEUTICALS INC (US) | 2016-04-27 | — | — | EP | disclosed |
| US-20150056160-A1 | CHEMICALLY INDUCED INTRACELLULAR HYPERTHERMIA | TEXAS PHARMACEUTICALS, INC. | 2015-02-26 | — | — | US | disclosed |
| US-20100056643-A1 | CHEMICALLY INDUCED INTRACELLULAR HYPERTHERMIA | ST. JUDE PHARMACEUTICALS, INC. | 2010-03-04 | — | — | US | disclosed |
| US-7635722-B1 | Chemical induced intracellular hyperthermia | Saint Jude Pharmaceuticals, Inc. (US) | 2009-12-22 | — | — | US | disclosed |
| EP-1098641-A4 | CHEMICALLY INDUCED INTRACELLULAR HYPERTHERMIA | ST JUDE PHARMACEUTICALS INC (US) | 2003-08-27 | — | — | EP | disclosed |
| EP-1098641-A1 | CHEMICALLY INDUCED INTRACELLULAR HYPERTHERMIA | Texas Pharmaceuticals, Inc. (US) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000006143-A1 | CHEMICALLY INDUCED INTRACELLULAR HYPERTHERMIA | TEXAS PHARMACEUTICALS, INC. (US) | 2000-02-10 | — | — | WO | disclosed |
| EP-0412211-A1 | Cancer therapy system | THERAPEUTICAL SYSTEMS CORPORATION (US) | 1991-02-13 | — | — | EP | disclosed |
| US-4935450-A | Cancer therapy system for effecting oncolysis of malignant neoplasms | THERAPEUTICAL SYSTEMS CORPORATION (US) | 1990-06-19 | — | — | US | disclosed |
| US-4724234-A | ADMINISTERING NUTRITIONAL REGIMEN AND AGENTS WHICH UNCOUPLE OXIDATIVE PHOSPHORYLATION | THERAPEUTICAL SYSTEMS CORP. (US) | 1988-02-09 | — | — | US | disclosed |
| US-4365019-A | INTEGRATED CIRCUITS | EASTMAN KODAK COMPANY (US) | 1982-12-21 | — | — | US | disclosed |