Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MLYCD | O95822 | 5/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4551014 | 0.81 | CHRNA7 (0.45) | ALDH1A1TSHRHSD17B10MLYCDNR1H4 | |
| SCHEMBL17571714 | 0.79 | TSHR (0.46) | HDAC1HDAC8HDAC6ALDH1A1TSHR | |
| SCHEMBL13457935 | 0.79 | HDAC1 (0.38) | HDAC1HDAC8HDAC6ALDH1A1TSHR | |
| SCHEMBL4197514 | 0.78 | ESR1 (0.43) | HDAC1HDAC8HDAC6ALDH1A1TSHR | |
| SCHEMBL54909 | 0.78 | CYP2C9 (0.50) | ALDH1A1CYP2C9CYP2D6HIF1AHPGD | |
| SCHEMBL3667690 | 0.77 | HDAC1 (0.37) | HDAC1HDAC8HDAC6ALDH1A1TSHR | |
| SCHEMBL537689 | 0.77 | PTPN5 (0.38) | HDAC1HDAC8HDAC6ALDH1A1TSHR | |
| SCHEMBL11298330 | 0.75 | CA2 (0.46) | HDAC1ALDH1A1TSHRMLYCDCA2 | |
| SCHEMBL17571721 | 0.75 | CA1 (0.48) | ALDH1A1TSHRKAT2BCA2HPGD | |
| SCHEMBL17571705 | 0.75 | HDAC6 (0.50) | HDAC1HDAC8HDAC6TSHRKAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642296-B2 | 2-hydroxy-1-(4-hydroxymethyl-phenyl)-2-methyl-propan-1-one, have higher reactivity at the benzylic hydroxy group and do not have a tendency to yellowing; photocurable composition for pigmented or non-pigmented varnish surface coatings | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-01-05 | — | — | US | disclosed |
| US-20070240609-A1 | Photoinitiators | IGM GROUP B.V. (NL) | 2007-10-18 | — | — | US | disclosed |
| EP-1763499-B1 | NEW PHOTOINITIATORS | CIBA SC HOLDING AG (CH) | 2007-09-26 | — | — | EP | disclosed |
| EP-1763499-A1 | NEW PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2007-03-21 | — | — | EP | disclosed |
| WO-2005100292-A1 | NEW PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-10-27 | — | — | WO | disclosed |