SCHEMBL4551014

SCHEMBL4551014

CN(C)C(c1ccc(C(=O)C(C)(C)O)cc1)c1ccc(C(=O)C(C)(C)O)cc1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 1/20 0.45
ALDH1A1 P00352 3/20 0.36
TSHR P16473 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CA2 P00918 1/20 0.34
MLYCD O95822 5/20 0.34
OPRD1 P41143 3/20 0.33
HPGD P15428 2/20 0.31
MAPT P10636 1/20 0.31
OPRM1 P35372 1/20 0.31
NR1H4 Q96RI1 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
HIF1A Q16665 1/20 0.31
FASN P49327 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4427237 0.84 CHRNA7 (0.44) CHRNA7ALDH1A1TSHRHSD17B10CA2
SCHEMBL3675439 0.81 HDAC1 (0.38) ALDH1A1TSHRHSD17B10CA2MLYCD
SCHEMBL4417620 0.81 OPRD1 (0.46) ALDH1A1TSHRCA2MLYCDOPRD1
SCHEMBL3102250 0.80 OPRD1 (0.40) ALDH1A1TSHRHSD17B10MLYCDOPRD1
SCHEMBL11298330 0.79 CA2 (0.46) ALDH1A1TSHRCA2MLYCDFASN
SCHEMBL4418465 0.79 MLYCD (0.36) ALDH1A1TSHRHSD17B10CA2MLYCD
SCHEMBL4423398 0.79 MLYCD (0.36) ALDH1A1TSHRHSD17B10MLYCDOPRD1
SCHEMBL4418946 0.79 MLYCD (0.33) ALDH1A1TSHRHSD17B10MLYCDOPRD1
SCHEMBL3671849 0.79 CA2 (0.37) ALDH1A1TSHRHSD17B10CA2MLYCD
SCHEMBL54909 0.79 CYP2C9 (0.50) ALDH1A1HPGDMAPTCYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1620475-B1 NOVEL TRIFUNCTIONAL PHOTOINITIATORS BASF SE (DE) 2009-11-11 EP disclosed
EP-1620475-A1 NOVEL TRIFUNCTIONAL PHOTOINITIATORS Ciba SC Holding AG (CH) 2006-02-01 EP disclosed
WO-2004099262-A1 NOVEL TRIFUNCTIONAL PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-11-18 WO disclosed