Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3072319 | 0.87 | EPHX1 (0.48) | HTR2ASLC6A4EPHX1ANPEPSLC6A2 | |
| SCHEMBL23420598 | 0.79 | HTR2A (0.50) | HTR2ASLC6A4SLC6A2TAAR1 | |
| SCHEMBL7513002 | 0.79 | HTR2A (0.50) | HTR2ASLC6A4EPHX1 | |
| SCHEMBL3672930 | 0.78 | SLC6A2 (0.52) | HTR2ASLC6A4SLC6A2TAAR1MAOA | |
| SCHEMBL11654244 | 0.78 | HTR2A (0.45) | HTR2ASLC6A4SLC6A2TAAR1MAOA | |
| SCHEMBL19712493 | 0.78 | HTR2A (0.53) | HTR2ASLC6A4EPHX1SLC6A2TAAR1 | |
| SCHEMBL23780015 | 0.78 | SLC6A4 (0.52) | HTR2ASLC6A4SLC6A2TAAR1SLC6A3 | |
| SCHEMBL9193881 | 0.77 | MMP1 (0.35) | SLC6A4SLC6A2TAAR1MAOASLC6A3 | |
| SCHEMBL7202017 | 0.73 | HTR2A (0.49) | HTR2A | |
| SCHEMBL943149 | 0.73 | GABRA1 (0.54) | HTR2ASLC6A4SLC6A2TAAR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1426392-B1 | COMPOSITION FOR OPTICAL MATERIAL | MITSUBISHI GAS CHEMICAL CO (JP) | 2010-02-24 | — | — | EP | disclosed |
| US-6960640-B2 | Composition for optical material | MITSUBISHI GAS CHEMICAL CO., LTD. (JP) | 2005-11-01 | — | — | US | disclosed |
| US-20040147708-A1 | Composition for optical material | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2004-07-29 | — | — | US | disclosed |
| EP-1426392-A1 | COMPOSITION FOR OPTICAL MATERIAL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2004-06-09 | — | — | EP | disclosed |