Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364354 | 0.84 | — | — | |
| SCHEMBL91254 | 0.83 | TSHR (0.40) | TSHRDNM1OPRM1CA2MAPK1 | |
| SCHEMBL22810400 | 0.81 | TSHR (0.39) | TSHRDNM1OPRM1CA2MAPK1 | |
| SCHEMBL27978858 | 0.81 | OPRM1 (0.41) | TSHRDNM1OPRM1CA2MAPK1 | |
| SCHEMBL13129918 | 0.81 | TSHR (0.39) | TSHRDNM1OPRM1CA2MAPK1 | |
| SCHEMBL11506838 | 0.80 | TSHR (0.48) | TSHRALDH1A1TDP1 | |
| SCHEMBL20758509 | 0.80 | LMNA (0.42) | TSHRMAPK1 | |
| SCHEMBL20822187 | 0.79 | OPRM1 (0.39) | TSHRDNM1OPRM1CA2 | |
| SCHEMBL10987090 | 0.79 | TSHR (0.46) | TSHRDNM1OPRM1FDPS | |
| SCHEMBL12475428 | 0.77 | DNM1 (0.36) | TSHRDNM1OPRM1CA2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7714087-B2 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof | MITSUI CHEMICALS, INC. (JP) | 2010-05-11 | — | — | US | disclosed |
| US-20090137757-A1 | Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof | IMUTA JUNICHI | 2009-05-28 | — | — | US | disclosed |