SCHEMBL3676327

SCHEMBL3676327

Cc1cccc([S+]([O-])c2cccc(C)c2C)c1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.42
ATM Q13315 1/20 0.42
TSHR P16473 3/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CYP2A6 P11509 2/20 0.38
CYP1A2 P05177 1/20 0.38
ACHE P22303 1/20 0.36
ALDH1A1 P00352 3/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
TDP1 Q9NUW8 1/20 0.34
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
MAPT P10636 2/20 0.32
RAPGEF4 Q8WZA2 1/20 0.32
GABRA1 P14867 1/20 0.32
GABRB2 P47870 1/20 0.32
CD44 P16070 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11196291 0.93 TRPA1 (0.38) TRPA1ATMTSHRSMN1; SMN2CYP2A6
SCHEMBL6916295 0.85 TRPA1 (0.35) TRPA1ATMTSHRSMN1; SMN2CYP2A6
SCHEMBL6312471 0.83 TRPA1 (0.41) TRPA1ATMTSHRSMN1; SMN2CYP2A6
SCHEMBL3190512 0.79 TRPA1 (0.46) TRPA1ATMTSHRSMN1; SMN2CYP2A6
SCHEMBL235850 0.79 TSHR (0.47) TSHRCYP2A6CYP1A2ACHEALDH1A1
SCHEMBL31005149 0.79 TRPA1 (0.46) TRPA1ATMTSHRSMN1; SMN2CYP2A6
SCHEMBL29468607 0.79 TSHR (0.47) TSHRCYP2A6CYP1A2ACHEALDH1A1
SCHEMBL6320850 0.78 TRPA1 (0.37) TRPA1ATMTSHRSMN1; SMN2CYP2A6
SCHEMBL3684645 0.77 CYP1A2 (0.31) TSHRCYP2A6CYP1A2
SCHEMBL7112346 0.76 ALDH1A1 (0.46) TSHRSMN1; SMN2CYP2A6CYP1A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2481760-B1 INITIATOR SYSTEM FOR CATIONIC POLYMERIZATION AND POLYMERIZATION METHOD USING SAME CHINA PETROLEUM & CHEM CORP (CN) 2021-05-05 EP claimed
CN-102532368-B Rare earth catalyst and method for polymerizing conjugated diene by using same UNIV BEIJING CHEMICAL 2014-04-02 CN claimed
CN-102532368-A Rare earth catalyst and method for polymerizing conjugated diene by using same UNIV BEIJING CHEMICAL 2012-07-04 CN claimed
CN-1288222-C Phosphorescent light-emitting material LAIDE SCIENCE & TECHNOLOGY CO (CN) 2006-12-06 CN claimed
CN-1464027-A Phosphorescent light-emitting material LAIDE SCIENCE & TECHNOLOGY CO (CN) 2003-12-31 CN claimed
US-12100809-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2024-09-24 US disclosed
EP-3848399-B1 TRANSITION METAL COMPOUND AND METHOD FOR PRODUCING OLEFIN POLYMER IDEMITSU KOSAN CO (JP) 2024-07-10 EP disclosed
EP-3681933-B1 POLYMER-METAL JUNCTION SOLVAY SPECIALTY POLYMERS USA (US) 2024-05-15 EP disclosed
CN-116162188-B Isobutene polymerization initiation system composition, polymerization method and application 浙江信汇新材料股份有限公司 2024-01-26 CN disclosed
US-11795188-B2 Transition metal compound and method for producing olefin polymer IDEMITSU KOSAN CO., LTD. (JP) 2023-10-24 US disclosed
CN-116162188-A Isobutene polymerization initiation system composition, polymerization method and application 浙江信汇新材料股份有限公司 2023-05-26 CN disclosed
US-11359120-B2 Polymer-metal junction SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2022-06-14 US disclosed
EP-1231236-A1 POLYPROPYLENE FILM AND MULTILAYERED LAMINATE IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-08-14 EP disclosed
EP-1231226-A1 ROLLED POLYPROPYLENE AND INJECTION-MOLDED POLYPROPYLENE IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-08-14 EP disclosed
EP-1227112-A1 PROPYLENE POLYMERS AND RESIN COMPOSITION AND MOLDING CONTAINING THE POLYMERS IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-07-31 EP disclosed
EP-1095951-A1 PROPYLENE POLYMER AND COMPOSITION CONTAINING THE SAME, MOLDED OBJECT AND LAMINATE COMPRISING THESE, AND PROCESSES FOR PRODUCING PROPYLENE POLYMER AND COMPOSITION CONTAINING THE SAME IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-05-02 EP disclosed
CN-1274433-A Radiation-sensitive compsn. of chemical amplification type containing onium salt type photosensitive acid generating agent CLARIANT INT LTD (CH) 2000-11-22 CN disclosed
US-5737102-A Method of making an optically nonlinear switched optical device and related devices UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 1998-04-07 US disclosed
US-5452123-A Method of making an optically nonlinear switched optical device and related devices UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 1995-09-19 US disclosed
WO-1993014084-A2 PIPERIDINE DERIVATIVES GLAXO GROUP LIMITED (GB) 1993-07-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11795188-B2 Transition metal compound and method for producing olefin polymer H1-0, C9, C5 TRPA1 1083/4885ATM 4656/4885TSHR 606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.