SCHEMBL3684645

SCHEMBL3684645

Cc1ccc([S+]([O-])c2ccc(C)c(C)c2C)c(C)c1C

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.31
CYP2A6 P11509 1/20 0.31
TSHR P16473 1/20 0.31
TDP2 O95551 1/20 0.31
NSD2 O96028 1/20 0.31
HSP90AA1 P07900 1/20 0.31
PAX8 Q06710 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3676327 0.77 TRPA1 (0.42) CYP1A2CYP2A6TSHR
SCHEMBL8662033 0.75 CYP3A4 (0.40) TSHR
SCHEMBL37955 0.72 TSHR (0.45) CYP1A2CYP2A6TSHRTDP2NSD2
SCHEMBL5494672 0.72 TSHR (0.45) CYP1A2CYP2A6TSHRTDP2NSD2
SCHEMBL2787911 0.72 ACHE (0.31)
SCHEMBL7108897 0.72 ACHE (0.33) CYP1A2CYP2A6TSHRTDP2NSD2
SCHEMBL11196291 0.72 TRPA1 (0.38) CYP1A2CYP2A6TSHR
SCHEMBL4131756 0.70 HPGD (0.35)
SCHEMBL10346182 0.69 TSHR (0.43) CYP1A2CYP2A6TSHRTDP2NSD2
SCHEMBL5181689 0.69 TSHR (0.43) CYP1A2CYP2A6TSHRTDP2NSD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3848399-B1 TRANSITION METAL COMPOUND AND METHOD FOR PRODUCING OLEFIN POLYMER IDEMITSU KOSAN CO (JP) 2024-07-10 EP disclosed
US-11795188-B2 Transition metal compound and method for producing olefin polymer IDEMITSU KOSAN CO., LTD. (JP) 2023-10-24 US disclosed
EP-3848399-A1 TRANSITION METAL COMPOUND AND METHOD FOR PRODUCING OLEFIN POLYMER Idemitsu Kosan Co., Ltd. (JP) 2021-07-14 EP disclosed
US-20210198300-A1 TRANSITION METAL COMPOUND AND METHOD FOR PRODUCING OLEFIN POLYMER IDEMITSU KOSAN CO.,LTD. (JP) 2021-07-01 US disclosed
EP-1867662-B2 Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same IDEMITSU KOSAN CO (JP) 2013-02-27 EP disclosed
EP-1231236-B1 POLYPROPYLENE FILM AND MULTILAYERED LAMINATE IDEMITSU KOSAN CO (JP) 2012-12-05 EP disclosed
EP-2028198-B1 Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containinig the same IDEMITSU KOSAN CO (JP) 2010-01-06 EP disclosed
US-20090215973-A1 PROPYLENE POLYMER AND COMPOSITION CONTAINING THE SAME, MOLDED OBJECT AND LAMINATE COMPRISING THESE, AND PROCESSES FOR PRODUCING PROPYLENE POLYMER AND COMPOSITION CONTAINING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-08-27 US disclosed
EP-1772467-B1 Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same IDEMITSU KOSAN CO (JP) 2009-08-05 EP disclosed
EP-1865006-B1 Propylene polymer and composition containing the same, molded object and laminate comprising these, and processes for producing propylene polymer and composition containing the same IDEMITSU KOSAN CO (JP) 2009-06-24 EP disclosed
EP-1227112-A1 PROPYLENE POLYMERS AND RESIN COMPOSITION AND MOLDING CONTAINING THE POLYMERS IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-07-31 EP disclosed
EP-1095951-A1 PROPYLENE POLYMER AND COMPOSITION CONTAINING THE SAME, MOLDED OBJECT AND LAMINATE COMPRISING THESE, AND PROCESSES FOR PRODUCING PROPYLENE POLYMER AND COMPOSITION CONTAINING THE SAME IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-05-02 EP disclosed
CN-1029398-C Process for preparing intermediates useful in the synthesis of steroids having optically active side chains WESONSIN ALUMNI RESEARCH FOUND (US) 1995-08-02 CN disclosed
EP-0386793-B1 NOVEL 1 ALPHA-HYDROXYVITAMIN D2 EPIMER AND DERIVATIVES WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1993-06-09 EP disclosed
US-5089647-A Method for preparing intermediates for the synthesis of steroid side chains in optically active form WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1992-02-18 US disclosed
CN-1048849-A Preparation is used for synthetic side chain and has the method for the intermediate of optically active steroide WISCONSIN ALUMNI RES FOUND (US) 1991-01-30 CN disclosed
US-4973584-A OSTEOPOROSIS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 1990-11-27 US disclosed
WO-1990010618-A1 METHOD FOR PREPARING INTERMEDIATES FOR THE SYNTHESIS OF STEROID SIDE CHAINS IN OPTICALLY ACTIVE FORM WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1990-09-20 WO disclosed
WO-1990010619-A1 NOVEL 1α-HYDROXYVITAMIN D2 EPIMER AND DERIVATIVES WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1990-09-20 WO disclosed
EP-0386794-A1 Method for preparing intermediates for the synthesis of steroid side chains in optically active form WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1990-09-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210198300-A1 TRANSITION METAL COMPOUND AND METHOD FOR PRODUCING OLEFIN POLYMER H1-0, C9, C5 CYP1A2 1949/4885CYP2A6 937/4885TSHR 606/4885
US-11795188-B2 Transition metal compound and method for producing olefin polymer H1-0, C9, C5 CYP1A2 1949/4885CYP2A6 937/4885TSHR 606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.