Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9161043 | 0.80 | MAPT (0.42) | CYP2C19KDM4EMAPTCYP3A4ALOX15 | |
| SCHEMBL5391094 | 0.79 | CYP2D6 (0.41) | LMNACYP2D6SRCALDH1A1TSHR | |
| SCHEMBL11044108 | 0.78 | IDO1 (0.34) | SMN1; SMN2LMNAHPGDALDH1A1USP2 | |
| SCHEMBL1052816 | 0.77 | TSHR (0.46) | CYP2C19KDM4EMAPTCYP3A4ALOX15 | |
| SCHEMBL5433742 | 0.77 | SMN1; SMN2 (0.35) | CYP2C19KDM4EMAPTCYP3A4ALOX15 | |
| SCHEMBL2007288 | 0.71 | KDM4E (0.53) | CYP2C19KDM4EMAPTCYP3A4ALOX15 | |
| SCHEMBL14938901 | 0.70 | LMNA (0.38) | CYP2C19CYP3A4LMNACYP2D6ALDH1A1 | |
| SCHEMBL8583801 | 0.69 | CYP2C19 (0.42) | CYP2C19KDM4EMAPTCYP3A4ALOX15 | |
| SCHEMBL250378 | 0.69 | CYP2C19 (0.42) | CYP2C19KDM4EMAPTCYP3A4ALOX15 | |
| SCHEMBL17075265 | 0.69 | CYP2C19 (0.42) | CYP2C19KDM4EMAPTCYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103200936-A | Novel N-hydroxybenzamide compounds for the treatment of cancer | HOFFMANN LA ROCHE | 2013-07-10 | — | — | CN | claimed |
| CN-102186809-A | Insecticidal 4-phenyl-1h-pyrazoles | BAYER CROPSCIENCE AG | 2011-09-14 | — | — | CN | claimed |
| EP-2348841-A1 | METHOD FOR IMPROVING PLANT HEALTH | BASF SE (DE) | 2011-08-03 | — | — | EP | claimed |
| EP-2348849-A1 | METHOD FOR IMPROVING PLANT HEALTH | BASF SE (DE) | 2011-08-03 | — | — | EP | claimed |
| CN-101965351-A | Benzofuran pyrimidinones | EXELIXIS INC | 2011-02-02 | — | — | CN | claimed |
| WO-2010049405-A1 | METHOD FOR IMPROVING PLANT HEALTH | BASF SE (DE) | 2010-05-06 | — | — | WO | claimed |
| US-20100113770-A1 | O-SUBSTITUTED HYDROXYARYL DERIVATIVES | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2010-05-06 | — | — | US | claimed |
| WO-2010049414-A1 | METHOD FOR IMPROVING PLANT HEALTH | BASF SE (DE) | 2010-05-06 | — | — | WO | claimed |
| CN-101027294-A | Phenyl DIAZEPAN carboxamides and annelated phenyl piperazine carboxamides containing oxygen and used as dopamine D3 antagonists | SANOL ARZNEI SCHWARZ GMBH (DE) | 2007-08-29 | — | — | CN | claimed |
| EP-1791825-A1 | BENZOYL-SUBSTITUTED SERINE AMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2007-06-06 | — | — | EP | claimed |
| CN-1107144-A | Substituted heterocyclic carboxamide esters, their preparation and their use as pharmaceuticals | HOECHST AG (DE) | 1995-08-23 | — | — | CN | claimed |
| WO-1994022859-A1 | SUBSTITUTED HETEROANNULATED IMIDAZOLES AND THEIR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1994-10-13 | — | — | WO | claimed |
| CN-1061414-A | HETEROAROYL DERIVATIVES OF MONOCYCLIC BETA-LACTAM ANTIBIOTICS | SQUIBB & SONS INC (US) | 1992-05-27 | — | — | CN | claimed |
| EP-0420069-A2 | Heterocyclic hydrazide derivatives of monocyclic beta-lactam antibiotics | E.R. SQUIBB & SONS, INC. (US) | 1991-04-03 | — | — | EP | claimed |
| EP-0114658-B1 | ALKYL-SUBSTITUTED 4-METHYL-PIPERIDINE DERIVATIVES AND USE THEREOF AS STABILIZERS | AUSIMONT S.p.A. (IT) | 1988-07-27 | — | — | EP | claimed |
| EP-0254078-A1 | Pyran derivatives | BASF Aktiengesellschaft (DE) | 1988-01-27 | — | — | EP | claimed |
| US-4621110-A | Alkyl-substituted 4-methyl-piperidine derivatives and use thereof as stabilizers | MONTEDISON S.P.A. (IT) | 1986-11-04 | — | — | US | claimed |
| EP-0114658-A1 | Alkyl-substituted 4-methyl-piperidine derivatives and use thereof as stabilizers | AUSIMONT S.p.A. (IT) | 1984-08-01 | — | — | EP | claimed |
| US-4289847-A | 2-EQUIVALENT YELLOW COUPLER | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1981-09-15 | — | — | US | claimed |
| US-4078061-A | ANDROSTENONES | RICHARDSON-MERRELL INC. (US) | 1978-03-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113770-A1 | O-SUBSTITUTED HYDROXYARYL DERIVATIVES | RELA, NFKBIA, NFE2 | CYP2C19 3634/4885KDM4E 2219/4885MAPT 4188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.