Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29424088 | 0.85 | ALDH1A1 (0.55) | LMNAALDH1A1CFTRHSD17B10MAPK8 | |
| SCHEMBL9851634 | 0.85 | ALDH1A1 (0.55) | LMNAALDH1A1CFTRHSD17B10MAPK8 | |
| SCHEMBL15528607 | 0.85 | ALDH1A1 (0.55) | LMNAALDH1A1CFTRHSD17B10MAPK8 | |
| SCHEMBL1035344 | 0.83 | ALDH1A1 (0.53) | LMNAALDH1A1CFTRHSD17B10MAPK8 | |
| SCHEMBL999348 | 0.83 | ABCB11 (0.51) | LMNAABCB11PTGS1ADORA1PTGS2 | |
| SCHEMBL1162462 | 0.83 | ALDH1A1 (0.60) | LMNAALDH1A1CFTRHSD17B10BCAT2 | |
| SCHEMBL15845989 | 0.82 | ALDH1A1 (0.51) | LMNAALDH1A1CFTRHSD17B10MAPK8 | |
| SCHEMBL8172682 | 0.82 | SMN1; SMN2 (0.48) | LMNAPTGS2ALDH1A1CFTRHSD17B10 | |
| Ethylene SCHEMBL7416648 | 0.82 | ALDH1A1 (0.45) | LMNAABCB11PTGS1ADORA1PTGS2 | |
| SCHEMBL28164371 | 0.81 | ABCB11 (0.59) | LMNAABCB11PTGS1ADORA1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103796992-A | Guanidinobenzoic acid compound | ASTELLAS PHARMA INC | 2014-05-14 | — | — | CN | claimed |
| EP-2400846-B1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARM INC (US) | 2016-10-05 | — | — | EP | disclosed |
| CN-102427731-B | Hepatitis c virus inhibitors | ENANTA PHARM INC | 2015-05-13 | — | — | CN | disclosed |
| CN-103796992-A | Guanidinobenzoic acid compound | ASTELLAS PHARMA INC | 2014-05-14 | — | — | CN | disclosed |
| US-8507522-B2 | Hepatitis C virus inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2013-08-13 | — | — | US | disclosed |
| US-20100260715-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2010-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100260715-A1 | HEPATITIS C VIRUS INHIBITORS | HAVCR2, SLC10A1, EIF2AK2 | LMNA 2800/4885ABCB11 23/4885PTGS1 760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.