Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3677282 | 0.88 | — | — | |
| SCHEMBL3683201 | 0.86 | HTR2A (0.33) | KDM4ELMNATP53CHRM2CYP3A4 | |
| SCHEMBL3684526 | 0.79 | HTR6 (0.36) | — | |
| SCHEMBL7105374 | 0.76 | HTR2A (0.47) | KDM4ELMNATP53CHRM2CYP3A4 | |
| SCHEMBL1453437 | 0.75 | HTR2A (0.42) | KDM4ELMNATP53CHRM2CYP3A4 | |
| SCHEMBL3683410 | 0.75 | HTR2A (0.35) | HTR2A | |
| SCHEMBL5954199 | 0.75 | HTR2A (0.36) | KDM4ELMNACHRM2CYP3A4CYP2D6 | |
| SCHEMBL12319663 | 0.75 | TAAR1 (0.46) | DRD2HTR2AHRH1DRD3 | |
| SCHEMBL4005225 | 0.74 | HTR2A (0.41) | KDM4ELMNATP53CHRM2CYP3A4 | |
| SCHEMBL1320258 | 0.74 | TAAR1 (0.42) | KDM4ELMNACHRM2CHRM1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8569532-B2 | Catalysts | BOREALIS TECHNOLOGY OY (FI) | 2013-10-29 | — | — | US | disclosed |
| US-20120252993-A1 | CATALYSTS | BOREALIS TECHNOLOGY OY (FI) | 2012-10-04 | — | — | US | disclosed |
| US-20100305286-A1 | CATALYSTS | BOREALIS TECHNOLOGY OY (FI) | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120252993-A1 | CATALYSTS | CYP4F11, COXFA4, CYP2F1 | KDM4E 4078/4885LMNA 3501/4885TP53 3485/4885 |
| US-20100305286-A1 | CATALYSTS | H1-2, CCNL2, H1-3 | KDM4E 2823/4885LMNA 1605/4885TP53 2353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.