SCHEMBL3684526

SCHEMBL3684526

CC1=Cc2cccc(CCC3C=Cc4ccccc43)c2C1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.36
SIGMAR1 Q99720 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3683201 0.79 HTR2A (0.33)
SCHEMBL3676744 0.79 KDM4E (0.30)
SCHEMBL7647636 0.77 PNMT (0.48) HTR6
SCHEMBL7613461 0.76 PNMT (0.47) HTR6
SCHEMBL7604393 0.76 PNMT (0.47) HTR6
Hydrochloric Acid SCHEMBL5346729 0.75 PNMT (0.46) HTR6
Hydrochloric Acid SCHEMBL5357721 0.75 PNMT (0.46) HTR6
SCHEMBL5954199 0.73 HTR2A (0.36)
SCHEMBL13905661 0.71 KDM4E (0.33)
SCHEMBL1319401 0.71 KDM4E (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8569532-B2 Catalysts BOREALIS TECHNOLOGY OY (FI) 2013-10-29 US disclosed
US-20120252993-A1 CATALYSTS BOREALIS TECHNOLOGY OY (FI) 2012-10-04 US disclosed
US-20100305286-A1 CATALYSTS BOREALIS TECHNOLOGY OY (FI) 2010-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120252993-A1 CATALYSTS CYP4F11, COXFA4, CYP2F1 HTR6 4500/4885SIGMAR1 648/4885
US-20100305286-A1 CATALYSTS H1-2, CCNL2, H1-3 HTR6 3352/4885SIGMAR1 84/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.