SCHEMBL3677100

SCHEMBL3677100

O=C(O)CNC(=O)c1cccc(O)c1O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 4/20 0.64
EGLN1 Q9GZT9 7/20 0.55
TERT O14746 2/20 0.54
FTO Q9C0B1 3/20 0.54
EGLN2 Q96KS0 1/20 0.54
KEAP1 Q14145 1/20 0.54
KDM5B Q9UGL1 1/20 0.45
KDM2A Q9Y2K7 1/20 0.45
BBOX1 O75936 1/20 0.45
MAPT P10636 2/20 0.45
NPC1 O15118 1/20 0.45
ALDH1A1 P00352 1/20 0.45
HPGD P15428 1/20 0.45
TSHR P16473 1/20 0.45
HTT P42858 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
HSD17B10 Q99714 1/20 0.45
NLRP1 Q9C000 1/20 0.45
KDM4E B2RXH2 1/20 0.44
HIF1A Q16665 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29387023 1.00 ALOX5 (0.64) ALOX5EGLN1TERTFTOEGLN2
Phosphoric Acid SCHEMBL10400886 0.95 ALOX5 (0.58) ALOX5EGLN1TERTFTOEGLN2
Salicyluric Acid SCHEMBL29935452 0.87 HPGD (0.58) EGLN1FTOEGLN2KEAP1KDM5B
SCHEMBL31099240 0.87 SELL (0.55) ALOX5EGLN1FTOEGLN2KEAP1
Salicyluric Acid SCHEMBL570541 0.87 HPGD (0.58) EGLN1FTOEGLN2KEAP1KDM5B
SCHEMBL21579702 0.84 ALOX5 (0.62) ALOX5EGLN1TERTMAPTNPC1
SCHEMBL13952095 0.82 ALOX5 (0.82) ALOX5TERTMAPTNPC1ALDH1A1
SCHEMBL12311981 0.82 MMP2 (0.59) ALOX5EGLN1FTOEGLN2KEAP1
SCHEMBL31448014 0.82 KEAP1 (0.62) EGLN1FTOEGLN2KEAP1MAPT
SCHEMBL26936095 0.81 ALOX5 (0.79) ALOX5TERTMAPTNPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 US disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 US disclosed
EP-3027754-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING enEvolv, Inc. (US) 2016-06-08 EP disclosed
WO-2015017866-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. (US) 2015-02-05 WO disclosed
EP-2044436-B1 METHODS AND COMPOSITIONS FOR DETECTION OF MICROORGANISMS AND CELLS AND TREATMENT OF DISEASES AND DISORDERS GENELUX CORP (US) 2014-06-04 EP disclosed
US-7820184-B2 Methods and compositions for detection of microorganisms and cells and treatment of diseases and disorders GENELUX CORPORATION (US) 2010-10-26 US disclosed
US-6013647-A BACTERICIDES GRUENENTHAL GMBH (DE) 2000-01-11 US disclosed
EP-0907633-A1 NEW SYNTHETIC CATECHOL DERIVATIVES, METHOD FOR PRODUCTION AND USE THEREOF Grünenthal GmbH (DE) 1999-04-14 EP disclosed
EP-0863139-A1 Benzoxazindione derivatives, process for their preparation and their use Grünenthal GmbH (DE) 1998-09-09 EP disclosed
WO-1997049670-A1 NEW SYNTHETIC CATECHOL DERIVATIVES, METHOD FOR PRODUCTION AND USE THEREOF Grünenthal GmbH (DE) 1997-12-31 WO disclosed
US-5554507-A IDENTIFYING POTENTIAL ANTIBIOTIC COMPOUNDS AGAINST MICROORGANISMS WITH ENTEROBACTER TYPE SIDEROPHORE AMERICAN CYANAMID COMPANY (US) 1996-09-10 US disclosed
US-5462969-A Administering a mixture of an iron chelator and pentamide NEW YORK UNIVERSITY (US) 1995-10-31 US disclosed
EP-0597185-A1 Bacillus subtilis siderophore genes AMERICAN CYANAMID COMPANY (US) 1994-05-18 EP disclosed
US-5302598-A Administering an iron chelator and trimethoprim/sulfamethoxazole to treat and prevent AIDS-related pneumonia NEW YORK UNIVERSITY (US) 1994-04-12 US disclosed
US-5158979-A Administering iron chelator NEW YORK UNIVERSITY (US) 1992-10-27 US disclosed
US-4590922-A INTRACELLULARLY LOCALIZING, THEN INDUCTINELY HEATING GORDON, DAVID, SKOKIE, ILLINOIS 1986-05-27 US disclosed