SCHEMBL3677409

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13570654	0.89	L3MBTL1 (0.58)	TSHRTRPA1ALDH1A1TDP1L3MBTL1
	SCHEMBL1066576	0.88	TSHR (0.67)	TSHRALDH1A1TDP1L3MBTL1LTA4H
	Hydrochloric Acid SCHEMBL1409425	0.86	TSHR (0.64)	TSHRALDH1A1TDP1L3MBTL1LTA4H
	SCHEMBL8089474	0.86	TSHR (0.71)	TSHRTRPA1ALDH1A1TDP1LTA4H
	Water SCHEMBL28780406	0.86	TSHR (0.64)	TSHRALDH1A1TDP1L3MBTL1LTA4H
	SCHEMBL13308081	0.85	TSHR (0.48)	TSHRTRPA1ALDH1A1TDP1L3MBTL1
	SCHEMBL3686733	0.85	TSHR (0.52)	TSHRTDP1L3MBTL1LTA4HNAAA
	SCHEMBL28716976	0.82	TSHR (0.54)	TSHRTDP1L3MBTL1LTA4HNAAA
	SCHEMBL1837574	0.82	ESR1 (0.54)	TSHRTDP1L3MBTL1CA2IDO1
	SCHEMBL5427137	0.82	TDP1 (0.64)	TSHRTRPA1ALDH1A1TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.