Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 3/20 | 0.31 |
| ▸ | SLC6A3 known ✓ | Q01959 | 3/20 | 0.31 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 5/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5909804 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL5909816 | 0.72 | ALDH1A1 (0.30) | ALDH1A1TSHRACHE | |
| Hydrochloric Acid SCHEMBL721919 | 0.72 | HTR2A (0.36) | HTR2CSLC6A2SLC6A3HTR2AHTR2B | |
| SCHEMBL1025201 | 0.71 | ALDH1A1 (0.36) | HTR2CMEN1ALDH1A1KMT2AHTR2A | |
| Hydrochloric Acid SCHEMBL7941112 | 0.71 | CYP1A2 (0.31) | HTR2CMEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL9440329 | 0.71 | CYP1A2 (0.31) | HTR2CMEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL4634124 | 0.71 | ALDH1A1 (0.33) | HTR2CMEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL1685540 | 0.69 | CYP1A2 (0.30) | HTR2C | |
| Hydrochloric Acid SCHEMBL2355025 | 0.69 | CYP1A2 (0.30) | HTR2C | |
| Hydrochloric Acid SCHEMBL2535196 | 0.69 | HTR2C (0.31) | HTR2CMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9469701-B2 | Polyethylene powder | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2016-10-18 | — | — | US | disclosed |
| US-20160137760-A1 | Polyethylene Powder | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2016-05-19 | — | — | US | disclosed |
| US-7807760-B2 | Process for producing ethylene-α-olefin copolymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-10-05 | — | — | US | disclosed |
| US-7504462-B2 | Process for producing olefin polymer | SUMITOMO CHEIMCAL COMPANY, LIMITED (JP) | 2009-03-17 | — | — | US | disclosed |
| US-7482409-B2 | Process for producing ethylene-α-olefin-polyene copolymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-01-27 | — | — | US | disclosed |
| US-20080214746-A1 | PROCESS FOR PRODUCING ETHYLENE-ALPHA-OLEFIN COPOLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-09-04 | — | — | US | disclosed |
| US-20080207852-A1 | PROCESS FOR PRODUCING ETHYLENE -ALPHA- OLEFIN COPOLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-08-28 | — | — | US | disclosed |
| US-20080182947-A1 | PROCESS FOR PRODUCING ETHYLENE -ALPHA- OLEFIN-POLYENE COPOLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-07-31 | — | — | US | disclosed |
| US-20080182949-A1 | PROCESS FOR PRODUCING OLEFIN POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-07-31 | — | — | US | disclosed |
| US-20060287449-A1 | Ultrahigh-molecular ethylene polymer | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2006-12-21 | — | — | US | disclosed |